| AQR | H. sapiens | PRP19 related | DKFZp686B23123, IBP160, KIAA0560, fSAP164 | 171.3 | 52 |
| PRPF8 | H. sapiens | U5 snRNP | HPRP8, PRP8, PRPC8, RP13 | 273.6 | 25 |
| SF3B1 | H. sapiens | 17S U2 snRNP | Hsh155, MDS, PRP10, PRPF10, SAP155 | 145.8 | 22 |
| SNRNP200 | H. sapiens | U5 snRNP | ASCC3L1, BRR2, FLJ11521, HELIC2, RP33 | 244.5 | 18 |
| MATR3 | H. sapiens | Occasionally detected in C complex | DKFZp686K0542, DKFZp686K23100, KIAA0723, MGC9105, MPD2 | 94.6 | 17 |
| QKI | H. sapiens | alternative splicing factor | DKFZp586I0923, Hqk, QK, QK1, QK3 | 37.7 | 17 |
| PTBP1 | H. sapiens | alternative splicing factor | HNRNP-I, HNRNPI, HNRPI, MGC10830, MGC8461 | 57.2 | 15 |
| SF3B3 | H. sapiens | 17S U2 snRNP | KIAA0017, RSE1, SAP130, SF3b130, STAF130 | 135.6 | 15 |
| HNRNPC | H. sapiens | hnRNP | C1, C2, HNRNP, HNRPC, MGC104306 | 33.7 | 14 |
| DHX8 | H. sapiens | Second step factors | DDX8, HRH1, PRP22, PRPF22 | 139.3 | 13 |
| XAB2 | H. sapiens | PRP19 related | DKFZp762C1015, HCNP, HCRN, NTC90, SYF1 | 100.0 | 13 |
| SF3B2 | H. sapiens | 17S U2 snRNP | Cus1, SAP145, SF3B145, SF3b1, SF3b150 | 100.2 | 11 |
| EFTUD2 | H. sapiens | U5 snRNP | DKFZp686E24196, FLJ44695, KIAA0031, MFDM, Snrp116 | 109.4 | 10 |
| CDC5L | H. sapiens | PRP19 complex | CDC5, CDC5-LIKE, CEF1, KIAA0432, PCDC5RP | 92.3 | 9 |
| PLRG1 | H. sapiens | PRP19 complex | Cwc1, MGC110980, PRL1, PRP46, PRPF46 | 57.2 | 7 |
| PRPF19 | H. sapiens | PRP19 complex | NMP200, PRP19, PSO4, SNEV, UBOX4 | 55.2 | 7 |
| EEF1A1 | H. sapiens | translation-related | CCS-3, CCS3, EE1A1, EEF-1, EEF1A | 50.1 | 6 |
| CRNKL1 | H. sapiens | PRP19 related | CLF, CRN, Clf1, HCRN, MSTP021 | 100.5 | 6 |
| RBM22 | H. sapiens | PRP19 related | Cwc2, FLJ10290, ZC3H16, fSAP47 | 46.9 | 6 |
| ISY1 | H. sapiens | PRP19 related | FSAP33, KIAA1160 | 33.0 | 6 |
| HNRNPA1 | H. sapiens | hnRNP | HNRPA1, HNRPA1L3, MGC102835, hnRNP A1, hnRNP-A1 | 38.7 | 5 |
| SNRPA1 | H. sapiens | 17S U2 snRNP | Lea1 | 28.4 | 5 |
| SRRM2 | H. sapiens | SR related | 300-KD, CWF21, Cwc21, DKFZp667L0421, DKFZp686O15166 | 299.6 | 5 |
| SNRPB2 | H. sapiens | 17S U2 snRNP | MGC24807, MGC45309, Msl1 | 25.5 | 4 |
| SF3A1 | H. sapiens | 17S U2 snRNP | PRP21, PRPF21, SAP114, SF3A120 | 88.9 | 4 |
| CDC40 | H. sapiens | Second step factors | EHB3, FLJ10564, MGC102802, PRP17, PRPF17 | 65.5 | 3 |
| HNRNPA0 | H. sapiens | hnRNP | HNRPA0 | 30.8 | 3 |
| SNRNP40 | H. sapiens | U5 snRNP | 40K, FLJ41108, HPRP8BP, MGC1910, PRP8BP | 39.3 | 3 |
| CWC22 | H. sapiens | Recruited at Bact complex | EIF4GL, KIAA1604, NCM, fSAPb | 105.5 | 3 |
| NOSIP | H. sapiens | Recruited at C complex | CGI-25 | 33.2 | 3 |
| HNRNPA2B1 | H. sapiens | hnRNP | DKFZp779B0244, FLJ22720, HNRNPA2, HNRNPB1, HNRPA2 | 37.4 | 2 |
| EIF4A3 | H. sapiens | EJC/mRNP | DDX48, DKFZp686O16189, KIAA0111, MGC10862, NMP265 | 46.9 | 2 |
| SNRPD1 | H. sapiens | Sm | HsT2456, SMD1, SNRPD, Sm-D1 | 13.3 | 2 |
| SNRPD3 | H. sapiens | Sm | SMD3, Sm-D3 | 13.9 | 2 |
| SNW1 | H. sapiens | PRP19 related | Bx42, MGC119379, NCOA-62, PRPF45, Prp45 | 61.5 | 2 |
| RBM7 | H. sapiens | pre-mRNA/mRNA binding proteins | FLJ11153 | 30.5 | 2 |
| BCAS2 | H. sapiens | PRP19 complex | DAM1, SPF27, Snt309 | 26.1 | 1 |
| COL1A1 | H. sapiens | | OI4 | 138.9 | 1 |
| SFPQ | H. sapiens | linked to splicing | DKFZp547C228, DKFZp667K0521, DKFZp686K1282, POMP100, PSF | 76.1 | 1 |
| SF3B4 | H. sapiens | 17S U2 snRNP | AFD1, Hsh49, MGC10828, SAP49, SF3b49 | 44.4 | 1 |
| ELAVL1 | H. sapiens | alternative splicing factor | ELAV1, HUR, Hua, MelG | 36.1 | 1 |
| PHF5A | H. sapiens | 17S U2 snRNP | INI, MGC1346, Rds3, SAP14b, SF3b14b | 12.4 | 1 |
| RALY | H. sapiens | hnRNP | HNRPCL2, MGC117312, P542 | 32.5 | 1 |
| PPIE | H. sapiens | PRP19 related | CYP-33, CYP33, MGC111222, MGC3736 | 33.4 | 1 |
| PPIL1 | H. sapiens | PRP19 related | CGI-124, CYPL1, MGC678, PPIase, hCyPX | 18.2 | 1 |
