Nomenclature

Gene Symbol
ELAVL1 (H. sapiens)
Other Gene Symbols
ELAV1, HUR, Hua, MelG
Full Name
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
Other Names
hUR, ELAV-like protein 1, Hu antigen R, embryonic lethal, abnormal vision, drosophila, homolog-like 1, hu-antigen R

Other Resources

Entrez: Gene Info
1994
Uniprot: Protein Info
ELAV1_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
108309
PDB: Structures
3HI9
SpliProt3D: Structural Model
ELAVL1

Gene Product Info

Molecular Weight (kD)
36.1
Domains
RRM
Motifs
—
Features
—
Class / Family
alternative splicing factor
Notes
—

Orthologs

Name Organism
F35H8.5 C. elegans
ELAVL1 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
ELAVL1 RBFOX2 Y2H: Prey/Bait 0.38 22365833
ELAVL1 PTBP1 Y2H: Prey/Bait 0.38 22365833
ELAVL1 PTBP2 Y2H: Prey/Bait 0.38 22365833
ELAVL1 ELAVL1 Y2H: Homodimer 0.33 22365833
ELAVL1 ELAVL1 Dervied from Literature — 15231747
ELAVL1 HNRNPK Y2H: Prey/Bait 0.4 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 77 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 77 24448447
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 52 18322460
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 36 24448447
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 24 21536652
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 21 18322460
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 18 21536652
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 14 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 14 24448447
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 11 17537823
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 11 27377154
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 10 16809785
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 9 20980672
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 9 21536652
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 5 16809785
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 4 17537823
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 4 18981222
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 3 11991638
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 3 11991638
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 3 16809785
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 2 17332742
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 2 27377154
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 1 21526149
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

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