Nomenclature
Gene Symbol
PTBP1 (H. sapiens )
Other Gene Symbols
HNRNP-I, HNRNPI, HNRPI, MGC10830, MGC8461
Full Name
polypyrimidine tract binding protein 1
Other Names
PTB, 57 kDa RNA-binding protein PPTB-1, RNA-binding protein, heterogeneous nuclear ribonucleoprotein I, heterogeneous nuclear ribonucleoprotein polypeptide I, hnRNP I
Other Resources
Entrez: Gene Info
5725 Uniprot: Protein Info
PTBP1_HUMAN Organism-Specific Database
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BioGrid: Interaction Info
111697 PDB: Structures
1QM9 , 1SJQ , 1SJR , 2AD9 , 2ADB SpliProt3D: Structural Model
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Gene Product Info
Molecular Weight (kD)
57.2
Domains
RRM
Motifs
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Features
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Class / Family
alternative splicing factor
Notes
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Identified in the following experiments:
Name Species # Of Peptides PubMed ID A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 36 18193060 E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 27 18193060 H complex, H. sapiens, (Jurica et al 2002) H. sapiens 15 11991638 C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 15 21526149 Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 12 17537823 Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 12 17537823 C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 6 19761775 Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060 E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060 C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 3 23345524 H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373 E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373 EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373 H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373 Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931 Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669 Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669 PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
