Nomenclature

Gene Symbol
PCBP1 (H. sapiens)
Other Gene Symbols
HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
Full Name
poly(rC) binding protein 1
Other Names
hnRNP E1, alpha-CP1, heterogeneous nuclear ribonucleoprotein E1, heterogenous nuclear ribonucleoprotein E1, heterogenous nuclear ribonucleoprotein X, nucleic acid-binding protein SUB2.3

Other Resources

Entrez: Gene Info
5093
Uniprot: Protein Info
PCBP1_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
111126
PDB: Structures
1WVN, 1ZTG, 3VKE
SpliProt3D: Structural Model
PCBP1

Gene Product Info

Molecular Weight (kD)
37.5
Domains
KH
Motifs
—
Features
—
Class / Family
hnRNP
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
PCBP1 PUF60 Dervied from Literature — 16713569
PCBP1 PRPF8 Pull-down — 22365833
PCBP1 PRPF8 Y2H: Prey/Bait 0.67 22365833
PCBP1 PRPF3 Y2H: Prey/Bait 0.5 22365833
PCBP1 ZNF830 Pull-down — 22365833
PCBP1 ZNF830 Y2H: Prey/Bait 0.5 22365833
PCBP1 PPIL3 Y2H: Prey/Bait 1 22365833
PCBP1 PPIG Pull-down — 22365833
PCBP1 PPIG Y2H: Prey/Bait 0.5 22365833
PCBP1 RBM42 Dervied from Literature — 16713569
PCBP1 SRSF3 Dervied from Literature — 16713569
PCBP1 PTBP1 Dervied from Literature — 16713569
PCBP1 MATR3 Dervied from Literature — 16713569
PCBP1 PCBP2 Dervied from Literature — 16713569
PCBP1 HNRNPD Dervied from Literature — 9234743
PCBP1 HNRNPK Dervied from Literature — 16713569
PCBP1 RALY Dervied from Literature — 16713569
PCBP1 QKI Dervied from Literature — 16713569
PCBP1 ZCCHC10 Y2H: Prey/Bait 1 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 58 21536652
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 42 18322460
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 17 18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 14 16809785
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 13 18322460
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 13 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 8 27377154
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 7 17537823
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 7 16809785
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 7 16809785
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 6 16809785
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 3 18981222
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 3 22110043
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447

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