Nomenclature

Gene Symbol
SRSF3 (H. sapiens)
Other Gene Symbols
SFRS3, SRp20
Full Name
serine/arginine-rich splicing factor 3
Other Names
SRp20, pre-mRNA-splicing factor SRP20, serine/arginine-rich splicing factor 3, splicing factor, arginine/serine-rich 3, splicing factor, arginine/serine-rich, 20-kD

Other Resources

Entrez: Gene Info
6428
Uniprot: Protein Info
SRSF3_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
112326
PDB: Structures
2I2Y, 2I38
SpliProt3D: Structural Model
SRSF3

Gene Product Info

Molecular Weight (kD)
19.3
Domains
RRM
Motifs
—
Features
—
Class / Family
SR protein
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SRSF3 PRPF38A Y2H: Prey/Bait 0.5 22365833
SRSF3 SRSF2 Y2H: Prey/Bait 0.67 22365833
SRSF3 SRPK1 Dervied from Literature — 8208298, 10390541
SRSF3 TRA2B Y2H: Prey/Bait 0.5 22365833
SRSF3 RBM7 Dervied from Literature — 12634307
SRSF3 PCBP2 Dervied from Literature — 17183366
SRSF3 PCBP1 Dervied from Literature — 16713569
SRSF3 HNRNPK Dervied from Literature — 10809782

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 23 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 22 18322460
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 22 17332742
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 19 16809785
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 18 18322460
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 15 18322460
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 12 24448447
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 12 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 11 24448447
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 10 16809785
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 8 17537823
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 8 18193060
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 8 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 6 18322460
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 6 27377154
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
mRNP on AdML, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 5 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 5 20980672
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 4 20980672
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 4 12226669
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 3 19761775
mRNP unspliced control, H. sapiens, (Merz et al 2007) H. sapiens 3 17095540
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 3 17537823
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934

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