Nomenclature

Gene Symbol
SRPK1 (H. sapiens)
Other Gene Symbols
SFRSK1
Full Name
SRSF protein kinase 1
Other Names
SRPK1, SFRS protein kinase 1, SR-protein-specific kinase 1, SRSF protein kinase 1, serine/arginine-rich splicing factor kinase 1, serine/threonine-protein kinase SRPK1

Other Resources

Entrez: Gene Info
6732
Uniprot: Protein Info
SRPK1_HUMAN
Organism-Specific Database
BioGrid: Interaction Info
112610
PDB: Structures
1WAK, 1WBP, 3BEG
SpliProt3D: Structural Model

Gene Product Info

Molecular Weight (kD)
74.3
Domains
Protein kinase
Motifs
Features
Class / Family
linked to splicing
Notes

Orthologs

Name Organism
SKY1 S. cerevisiae
dsk1 S. pombe
B0464.5 C. elegans
SRPK1 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SRPK1 SNRNP70 Dervied from Literature 9472028, 12417631
SRPK1 U2AF1 Dervied from Literature 9472028
SRPK1 U2AF1 Y2H: Bidirectional 1 22365833
SRPK1 U2AF2 Dervied from Literature 8798720
SRPK1 PRPF40A Dervied from Literature 9171351
SRPK1 PRPF38A Y2H: Bait/Prey 0.67 22365833
SRPK1 SRSF1 Dervied from Literature 8208298, 8798720, 9472028, 10196197, 10390541, 12565863, 17517895
SRPK1 SRSF2 Dervied from Literature 8798720
SRPK1 SRSF4 Dervied from Literature 8208298, 10390541
SRPK1 SRSF5 Dervied from Literature 8208298, 10390541
SRPK1 SRSF6 Dervied from Literature 8208298, 8798720
SRPK1 SRPK1 Dervied from Literature 8208298, 10390541, 12660167
SRPK1 SRSF3 Dervied from Literature 8208298, 10390541

view interactions at SSPPIR...

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