Links to Cryo-EM structures of spliceosomes
(updated Dec 2022)
Primary EMD- entry | Complex | Organism | Lab | Resolution | PDB model | Related EMD- Maps |
EMD-6915 | SF3B complex with E7107 | Human | Larsen | 4.0 Å | 5zya | |
EMD-31330 | SF3B complex with DDX42 | Human | Shi | 2.6 Å | 7evn | |
EMD-8622 | U1snRNP | S. cerevisiae | Zhao | 3.7Å | 5uz5 | |
EMD-10688 | 17S U2 snRNP | Human | Lührmann/Stark | 7.1 Å | 6Y5Q | 10689 |
EMD-10689 | 17S U2 snRNP 5' domain | Human | Lührmann/Stark | 4.1 Å | 6Y50 | 10688 |
EMD-10688 | 17S U2 snRNP lower resolution region | Human | Lührmann/Stark | 7.1 Å | 6Y53 | 10689 |
EMD-31334 | 17S U2 snRNP | Human | Shi | 2.5 Å | 7evo | |
EMD-13793 | 17S U2 snRNP 5' domain | Human | Galej | 2.2 Å | 7q3l | |
EMD-13812 | U2 snRNP after ATP remodeling | Human | Galej | 2.2 Å | 7q4p | |
EMD-1847 | U5 35S complex | Human | Lührmann/Stark | 27.8Å | na | 1847 |
EMD-2966 | tri-snRNP | S. cerevisiae | Nagai | 5.9Å | na | 2966 |
EMD-8012 | tri-snRNP | S. cerevisiae | Nagai | 3.7Å | 5gan | 8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014 |
EMD-6561 | tri-snRNP | S. cerevisiae | Shi | 3.81Å | 3jcm | 6561, 6562, 6563, 6564, 6565, 6566, 6567, 6568, 6569, 6570, 6571, 6572, 6573 |
EMD-8014 | tri-snRNP, body region | S. cerevisiae | Nagai | 3.6Å | 5gap | 8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014 |
EMD-8011 | tri-snRNP, foot region | S. cerevisiae | Nagai | 3.7Å | 5gam | 8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014 |
EMD-8013 | tri-snRNP, head region | S. cerevisiae | Nagai | 4.2Å | 5gao | 8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014 |
EMD-0360 | E complex on UBC4 intron | S. cerevisiae | Zhao | 3.6Å | 6n7p | |
EMD-0361 | E complex on ACT1 intron | S. cerevisiae | Zhao | 3.2Å | 6n7r | |
EMD-13033 | pre-A complex | S. cerevisiae | Lührmann/Stark | 5.9 Å | 7oqe | 13030, 13031, 13032 |
EMD-13028 | pre-A complex U2 snRNP portion | S. cerevisiae | Lührmann/Stark | 9 Å | 7oqb | 13030, 13031, 13032 |
EMD-13029 | pre-A complex U1 snRNP portion | S. cerevisiae | Lührmann/Stark | 4.1 Å | 7oqc | 13030, 13031, 13032 |
EMD-12994 | SSA-bound A complex U2 snRNP 5' module | Human | Pena | 3.1 Å | 7onb | |
EMD-13811 | A-like U2 snRNP bound to BP oligo | Human | Galej | 2.1 Å | 7q4o | |
EMD-4364 | A complex | S. cerevisiae | Nagai | 4.0 Å | 6g90 | 4363, 4365, |
EMD-3682 | Pre-B complex | S. cerevisiae | Nagai | 3.9 Å | 5nrl | 3682, 3683, 3684, 3685, 3686, 3687, 3688 |
EMD-4665 | Pre-B complex | Human | Nagai | 3.3 Å | 6qx9 | |
EMD-9621 | Pre-B complex | Human | Shi | 5.7 Å | 6ah0 | |
EMD-6973 | Pre-B complex: U1 snRNP region) | S. cerevisiae | Shi | 3.4 Å | 5zwm | |
EMD-6974 | B complex | S. cerevisiae | Shi | 3.9 Å | 5zwo | |
EMD-9624 | B complex | Human | Shi | 3.8 Å | 6ahd | |
EMD-1066 | B complex | Human | Lührmann/Stark | 40 Å | na | 1066 |
EMD-3766 | B complex | Human | Lührmann/Stark | 4.5 Å | 5o9z | 3766, 3767, 3768, 3769 |
EMD-11694 | pre-Bact-1 core | Human | Lührmann/Stark | 3.9 Å | 7abf | 11693, 11695, 11696 |
EMD-11695 | pre-Bact-1 | Human | Lührmann/Stark | 7.8 Å | 7abg | 11693, 11694, 11696 |
EMD-11693 | pre-Bact-2 core | Human | Lührmann/Stark | 4.2 Å | 7aav | 11694, 11695, 11696 |
EMD-11696 | pre-Bact-2 (SF3b/U2 snRNP portion) | Human | Lührmann/Stark | 4.5 Å | 7abh | 11693, 11694, 11695 |
EMD-11697 | pre-Bact-2 | Human | Lührmann/Stark | 8.0 Å | 7abi | |
EMD-9524 | Bact complex | S. cerevisiae | Shi | 3.5 Å | 5gm6 | |
EMD-4099 | Bact complex | S. cerevisiae | Lührmann/Stark | 5.8 Å | 5lqw | 4099 |
EMD-4254 | Bact complex | Human | Lührmann/Stark | 3.7 Å | na | 4233-4240, 4247-4252 |
EMD-4240 | Bact core | Human | Lührmann/Stark | 4.5 Å | 6ff7 | |
EMD-4255 | Bact core | Human | Lührmann/Stark | 3.4 Å | 6ff4 | |
EMD-6891 | Bact-1 complex | Human | Shi | 4.9 Å | 5z58 | |
EMD-6889 | Bact-2 complex | Human | Shi | 5.1 Å | 5z56 | |
EMD-6890 | Bact-3 complex | Human | Shi | 6.5 Å | 5z57 | |
EMD-30637 | Bact complex | S. cerevisiae | Shi | 2.5 Å | 7dco | 12107-12117 |
EMD-30875 | Bact complex Minor spliceosome | Human | Shi | 2.9 Å | 7dvq | 30875, 30879 |
EMD-0687 | B*-a1 complex | S. cerevisiae | Shi | 3.6 Å | 6j6h | 0684,0685,0686,0691,0692 |
EMD-0686 | B*-a2 complex | S. cerevisiae | Shi | 3.2 Å | 6j6g | 0684,0685,0687,0691,0692 |
EMD-0691 | B*-b1 complex | S. cerevisiae | Shi | 3.9 Å | 6j6n | 0684,0685,0686,0687,0692 |
EMD-0692 | B*-a2 complex | S. cerevisiae | Shi | 3.7 Å | 6j6q | 0684,0685,0686,0691,0687 |
EMD-12106 | C complex with Prp18/Slu7 | S. cerevisiae | Nagai | 2.8 Å | 7b9v | 12107-12117 |
EMD-4055 | C complex | S. cerevisiae | Nagai | 3.8 Å | 5lj3 | 4055, 4056, 4057, 4058, 4059 |
EMD-4057 | C complex | S. cerevisiae | Nagai | 10 Å | 5lj5 | 4055, 4056, 4057, 4058, 4059 |
EMD-9525 | C complex | S. cerevisiae | Shi | 3.4 Å | 5gmk | 9525, 9526, 9527 |
EMD-11569 | C complex core | Human | Lührmann/Stark | 3.4 Å | 6zym | 11570 |
EMD-11570 | C complex periphery | Human | Lührmann/Stark | 5 Å | 7a5p | 11569 |
EMD-6864 | C complex | Human | Shi | 4.1 Å | 5yzg | |
EMD-1846 | C complex | Human | Lührmann/Stark | 29 Å | na | 1846 |
EMD-1062 | C complex | Human | Moore/Grigorieff | 30 Å | na | 1062 |
EMD-1848 | C complex, high salt core | Human | Lührmann/Stark | na | na | 1848 |
EMD-32317 | pre-C*-I complex | Human | Shi | 3.6 Å | 7w59 | |
EMD-32319 | pre-C*-II complex | Human | Shi | 3.6 Å | 7w5a | |
EMD-32321 | C* complex | Human | Shi | 4.3 Å | 7w5b | |
EMD-3539 | C* complex | S. cerevisiae | Nagai | 3.9 Å | 5mps | 3539, 3541, 3542 |
EMD-3541 | C* complex | S. cerevisiae | Nagai | 4.2 Å | 5mq0 | 3539, 3541, 3542 |
EMD-6684 | C* complex | S. cerevisiae | Shi | 4 Å | 5wsg | 6684 |
EMD-3545 | C* complex | Human | Lührmann/Stark | 5.9 Å | 5mqf | 3545, 3547 |
EMD-6721 | C* complex | Human | Shi | 3.6Å | 5xjc | 6721 |
EMD-7109 | P complex | S. cerevisiae | Zhao | 3.3 Å | 6bk8 | |
EMD-3979 | P w/ 3' SS docked | S. cerevisiae | Nagai | 3.7 Å | 6exn | 3980 |
EMD-3980 | P w/ 3' SS undocked | S. cerevisiae | Nagai | 4 Å | None | 3979 |
EMD-6839 | P complex | S. cerevisiae | Shi | 3.6 Å | 5ylz | |
EMD-4525 | P complex | Human | Nagai | 3.3 Å | 6qdv | |
EMD-9645 | P complex | Human | Shi | 3.0 Å | 6icz | |
EMD-6413 | Released intron complex | S. pombe | Shi | 3.6 Å | 3jb9 | 6413, 6414, 6415, 6416, 6417, 6418, 6419, 6420, 6421 |
EMD-6817 | Released intron complex | S. cerevisiae | Shi | 3.5 Å | 5y88 | |
EMD-9646 | Released intron complex | Human | Shi | 2.9 Å | 6id0 | |
EMD-9647 | Released intron complex w/ Prp43 | Human | Shi | 2.9 Å | 6id1 | |
EMD-1294 | Supraspliceosome | Human | Sperling | 22 Å | na | 1294 |