Links to Cryo-EM structures of spliceosomes

(updated Mar 2021)

Primary EMD entryComplexOrganismLabResolutionPDB modelRelated EMD Maps
EMD-6915SF3B complex with E7107HumanLarsen3.95 Å5zya
EMD-8622U1snRNPS. cerevisiaeZhao3.7 Å6n7x
EMD-10689U2snRNPHumanLührmann/Stark7.1 Å6y5q
EMD-10689U2snRNPHumanLührmann/Stark7.1 Å6y53
EMD-1847U5 35S complexHumanLührmann/Stark27.8 Åna1847
EMD-2966tri-snRNPS. cerevisiaeNagai5.9 Åna2966
EMD-8012tri-snRNPS. cerevisiaeNagai3.7 Å5gan8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014
EMD-6561tri-snRNPS. cerevisiaeShi3.81 Å3jcm6561, 6562, 6563, 6564, 6565, 6566, 6567, 6568, 6569, 6570, 6571, 6572, 6573"
EMD-8014tri-snRNP, body regionS. cerevisiaeNagai3.6 Å5gap8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014
EMD-8011tri-snRNP, foot regionS. cerevisiaeNagai3.7 Å5gam8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014
EMD-8013tri-snRNP, head regionS. cerevisiaeNagai4.2 Å5gao8006, 8007, 8008, 8009, 8010, 8012, 8011, 8013, 8014
EMD-6581tri-snRNPHumanLührmann/Stark7 Å3jcr
EMD-4658tri-snRNPHumanNagai2.92 Å6qw64672, 4673, 4674, 4675, 4676, 4686
EMD-0360E complex on UBC4 intronS. cerevisiaeZhao3.6 Å6n7p
EMD-0361E complex on ACT1 intronS. cerevisiaeZhao3.2 Å6n7r
EMD-4364A complexS. cerevisiaeNagai4.0 Å6g904363, 4365
EMD-6972Pre-B complex: U2/tri snRNP regionS. cerevisiaeShi3.4 Å5zwm
EMD-6973Pre-B complex: U1 snRNP regionS. cerevisiaeShi3.4 Å5zwn
EMD-4665Pre-B complexHumanNagai3.28 Å6qx94687,4688,4689,4690
EMD-9621Pre-B complexHumanShi5.7 Å6ah0
EMD-3682B complexS. cerevisiaeNagai3.9 Å5nrl3682, 3683, 3684, 3685, 3686, 3687, 3688
EMD-6974B complexS. cerevisiaeShi3.9 Å5zwo
EMD-1066B complexHumanLührmann/Stark40 Åna1066
EMD-3766B complexHumanLührmann/Stark4.5Å5o9z3766, 3767, 3768, 3769
EMD-9624B complexHumanShi3.8 Å6ahd
EMD-11695pre-Bact1 complexHumanLührmann/Stark7.8 Å7abg11693,1694,11696,11697
EMD-11694pre-Bact1 coreHumanLührmann/Stark3.9 Å7abf11693,11695,11696,11697
EMD-11697pre-Bact2 complexHumanLührmann/Stark8.0 Å7abi11693,11694,11695,11696
EMD-11693pre-Bact2 coreHumanLührmann/Stark4.2 Å7aav11694,11695,11696,11697
EMD-11696pre-Bact2 (SF3b/U2 snRNP portion)HumanLührmann/Stark4.5 Å7abh11693,11694,11695,11697
EMD-30637Bact complexS. cerevisiaeShi2.5 Å7dco
EMD-9524Bact complexS. cerevisiaeShi3.5 Å5gm6
EMD-4099Bact complexS. cerevisiaeLührmann/Stark5.8 Å5lqw4099
EMD-4254Bact complexHumanLührmann/Stark3.7 Åna4233-4240, 4247-4252
EMD-4255Bact coreHumanLührmann/Stark3.4 Å6ff4
EMD-4240Bact coreHumanLührmann/Stark4.5 Å6ff7
EMD-6891Bact-1 complexHumanShi4.9 Å5z58
EMD-6889Bact-2 complexHumanShi5.1 Å5z56
EMD-6890Bact-3 complexHumanShi6.5 Å5z57
EMD-0687B*-a1 complexS. cerevisiaeShi3.6 Å6j6h0684,0685,0686,0691,0692
EMD-0686B*-a2 complexS. cerevisiaeShi3.2 Å6j6g0684,0685,0687,0691,0692
EMD-0691B*-b1 complexS. cerevisiaeShi3.86 Å6j6n0684,0685,0686,0687,0692
EMD-0692B*-a2 complexS. cerevisiaeShi3.7 Å6j6q0684,0685,0686,0687,0691
EMD-12106C complexS. cerevisiaeNagai2.8 Å7b9v
EMD-4055C complexS. cerevisiaeNagai3.8 Å5lj34055, 4056, 4057, 4058, 4059
EMD-4057C complexS. cerevisiaeNagai10 Å5lj54055, 4056, 4057, 4058, 4059
EMD-9525C complexS. cerevisiaeShi3.4 Å5gmk9525, 9526, 9527
EMD-11569C complex coreHumanLührmann/Stark3.40 Å6zym11570,11571,11572,11573,11574
EMD-6864C complexHumanShi4.1 Å5yzg
EMD-1846C complexHumanLührmann/Stark29 Åna1846
EMD-1062C complexHumanMoore/Grigorieff30 Åna1062
EMD-1848C complex, high salt coreHumanLührmann/Starknana1848
EMD-3539C* complexS. cerevisiaeNagai3.85 Å5mps3539, 3541, 3542
EMD-3541C* complexS. cerevisiaeNagai4.17 Å5mq03539, 3541, 3542
EMD-6684C* complexS. cerevisiaeShi4 Å5wsg6684
EMD-3545C* complexHumanLührmann/Stark5.9 Å5mqf3545, 3547
EMD-6721C* complexHumanShi3.6 Å5xjc6721
EMD-7109P complexS. cerevisiaeZhao3.3 Å6bk8
EMD-3979P complex w/ 3' SS dockedS. cerevisiaeNagai3.7 Å6exn3980
EMD-3980P complex w/ 3' SS undockedS. cerevisiaeNagai4 ÅNone3979
EMD-6839P complexS. cerevisiaeShi3.6 Å5ylz
EMD-4525P complexHumanNagai3.3 Å6qdv
EMD-9645P complexHumanShi3.0 Å6icz
EMD-6413Released intron complexS. pombeShi3.6Å3jb96413, 6414, 6415, 6416, 6417, 6418, 6419, 6420, 6421
EMD-6817Released intron complexS. cerevisiaeShi3.46 Å5y88
EMD-9646Released intron complexHumanShi2.9 Å6id0
EMD-9647Released intron complex w/ Prp43HumanShi2.9 Å6id1
EMD-1294SupraspliceosomeHumanSperling22 Åna1294

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