Nomenclature

Gene Symbol
SRSF5 (H. sapiens)
Other Gene Symbols
HRS, SFRS5, SRP40
Full Name
serine/arginine-rich splicing factor 5
Other Names
SRp40, SR splicing factor 5, delayed-early protein HRS, pre-mRNA-splicing factor SRP40, serine/arginine-rich splicing factor 5, splicing factor, arginine/serine-rich 5

Other Resources

Entrez: Gene Info
6430
Uniprot: Protein Info
SRSF5_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
112328
PDB: Structures
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SpliProt3D: Structural Model
SRSF5

Gene Product Info

Molecular Weight (kD)
31.3
Domains
RRM
Motifs
—
Features
—
Class / Family
SR protein
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SRSF5 SNRPF Y2H: Prey/Bait 0.5 22365833
SRSF5 SRSF1 Dervied from Literature — 9799243
SRSF5 SRPK1 Dervied from Literature — 8208298, 10390541

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 113 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 94 21536652
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 32 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 27 24448447
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 24 18322460
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 21 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 20 24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 17 27377154
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 16 16809785
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 16 27377154
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 15 20980672
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 15 27377154
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 13 17332742
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 12 18322460
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 11 16809785
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 11 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 9 16809785
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 5 20980672
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 5 22110043
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 4 20980672
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 4 16809785
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 3 18322460
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
H complex, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934

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