Nomenclature

Gene Symbol
SNRPF (H. sapiens)
Other Gene Symbols
SMF, Sm-F, snRNP-F
Full Name
small nuclear ribonucleoprotein polypeptide F
Other Names
SmF1, sm protein F, small nuclear ribonucleoprotein F

Other Resources

Entrez: Gene Info
6636
Uniprot: Protein Info
RUXF_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
112520
PDB: Structures
2Y9A, 2Y9B, 2Y9C, 2Y9D, 3CW1
SpliProt3D: Structural Model
SNRPF

Gene Product Info

Molecular Weight (kD)
9.7
Domains
—
Motifs
—
Features
—
Complex Association
17S U2 snRNP, A complex, B complex, Bact complex, C complex, P complex, tri-snRNP, U1 snRNP, U4/U6 snRNP, U5 snRNP
Class / Family
Sm
Notes
—

Orthologs

Name Organism
SMX3 S. cerevisiae
smf1 S. pombe
SmF D. melanogaster
ZK652.1 C. elegans
SNRPF G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SNRPF SNRPD2 Dervied from Literature — 9417867, 11226169
SNRPF SNRPD2 Y2H: Bidirectional 1 22365833
SNRPF SNRPE Dervied from Literature — 9417867, 11226169
SNRPF SNRPE Y2H: Bidirectional 1 22365833
SNRPF SNRPG Y2H: Bait/Prey 1 22365833
SNRPF SNRPG Dervied from Literature — 9417867
SNRPF LSM5 Dervied from Literature — 15231747
SNRPF LSM5 Y2H: Bidirectional 0.89 22365833
SNRPF LSM6 Y2H: Bait/Prey 1 22365833
SNRPF LSM7 Y2H: Bait/Prey 1 22365833
SNRPF SNRPA1 Y2H: Bait/Prey 1 22365833
SNRPF PUF60 Y2H: Bait/Prey 0.72 22365833
SNRPF SRSF5 Y2H: Bait/Prey 0.5 22365833
SNRPF SRRT Y2H: Bait/Prey 1 22365833
SNRPF SMN1 Dervied from Literature — 10556282

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 418 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 335 21536652
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 274 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 239 21536652
17S U2 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 203 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 202 21536652
U1 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 187 21536652
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 117 21386897
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 89 21386897
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 82 21386897
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 23 18322460
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 21 18322460
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 20 19941820
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 19 24448447
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 15 19935684
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 13 18981222
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 11 18322460
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 11 18981222
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 11 16809785
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 11 24448447
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 11 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 9 19941820
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 9 20980672
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 9 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 9 19935684
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 8 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 8 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 8 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 6 18322460
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 6 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 6 20980672
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 5 20980672
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 5 16809785
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 5 22110043
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 5 23431055
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 5 23431055
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 4 19941820
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 4 19941820
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 4 17537823
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 4 23345524
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 3 16809785
Prp8 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 3 19789211
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 3 24448447
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
U2/U5/U6 complex Snt309-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 2 11804584
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 2 19941820
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 2 17332742
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 2 11884590
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 2 17537823
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 2 21526149
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 1 18322460
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 1 19761775
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
Clf1p-pulldown, S. cerevisiae, (Wang et al 2003) S. cerevisiae 1 12509417
Cwc21 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 1 19789211
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae ■ 10449419
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
U11/U12 18S di-snRNP, H. sapiens, (Will et al 2004) H. sapiens ■ 15146077
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
tri-snRNP, S. cerevisiae, (Stevens et al 1999) S. cerevisiae ■ 11720284
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
A-like complex (A') Weri, H. sapiens, (Sharma et al 2008) H. sapiens ■ 18193060
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
U1 snRNP, S. pombe, (Newo et al 2007) S. pombe ■ 17264129
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe ■ 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, without splicing substrate, 250 mM salt wash, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, 250 mM salt wash, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

©2011 Spliceosome Component Database  All Rights Reserved.
design by juricalab