Nomenclature

Gene Symbol
LSM7 (H. sapiens)
Other Gene Symbols
YNL147W
Full Name
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Other Names
LSM7, U6 snRNA-associated Sm-like protein LSm7

Other Resources

Entrez: Gene Info
51690
Uniprot: Protein Info
LSM7_HUMAN
Organism-Specific Database
BioGrid: Interaction Info
119678
PDB: Structures
SpliProt3D: Structural Model
LSM7

Gene Product Info

Molecular Weight (kD)
11.6
Domains
Motifs
Features
Complex Association
B complex, tri-snRNP
Class / Family
LSm
Notes

Orthologs

Name Organism
LSM7 S. cerevisiae
lsm7 S. pombe
LSm7 D. melanogaster
ZK593.7 C. elegans
PFL0460w P. falciparum
LSM7 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
LSM7 SNRPD3 Dervied from Literature 15231747
LSM7 SNRPD3 Y2H: Prey/Bait 1 22365833
LSM7 SNRPF Y2H: Prey/Bait 1 22365833
LSM7 LSM2 Dervied from Literature 14667819, 15231747
LSM7 LSM2 Y2H: Prey/Bait 1 22365833
LSM7 LSM3 Dervied from Literature 15231747
LSM7 LSM3 Y2H: Prey/Bait 1 22365833
LSM7 LSM4 Dervied from Literature 15231747
LSM7 LSM4 Y2H: Bidirectional 1 22365833
LSM7 LSM5 Dervied from Literature 11591653, 15231747
LSM7 LSM5 Y2H: Bidirectional 0.89 22365833
LSM7 LSM6 Dervied from Literature 15231747
LSM7 LSM6 Y2H: Prey/Bait 0.67 22365833
LSM7 LSM8 Dervied from Literature 15231747
LSM7 SMN1 Dervied from Literature 10851237

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 83 21536652
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 79 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 18 21536652
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 9 19935684
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 6 16809785
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 6 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 5 19935684
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 4 16809785
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 4 24448447
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 4 24448447
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 3 19941820
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 3 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 3 16809785
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 2 11804584
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 2 18981222
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae 10449419
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens 12176931
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 24448447

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