Nomenclature

Gene Symbol
SRRT (H. sapiens)
Other Gene Symbols
ARS2, ASR2, MGC126427, serrate
Full Name
serrate RNA effector molecule homolog (Arabidopsis)
Other Names
ASR2B, arsenate resistance protein 2, arsenate resistance protein ARS2, arsenite resistance protein, arsenite-resistance protein 2, serrate RNA effector molecule homolog

Other Resources

Entrez: Gene Info
51593
Uniprot: Protein Info
SRRT_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
119626
PDB: Structures
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SpliProt3D: Structural Model
ARS2

Gene Product Info

Molecular Weight (kD)
100.7
Domains
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Motifs
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Features
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Class / Family
pre-mRNA/mRNA binding proteins
Notes
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Orthologs

Name Organism
Ars2 D. melanogaster
E01A2.2 C. elegans

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SRRT SNRPF Y2H: Prey/Bait 1 22365833
SRRT HSPA8 Y2H: Bait/Prey 0.62 22365833
SRRT HNRNPK Y2H: Bait/Prey 0.5 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 154 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 94 27377154
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 91 18322460
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 81 16809785
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 69 16809785
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 69 21536652
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 62 27377154
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 56 20980672
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 55 21536652
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 54 27377154
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 52 21536652
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 50 18981222
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 47 16809785
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 39 18193060
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 33 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 33 27377154
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 32 21536652
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 31 18322460
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 29 18981222
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 27 17332742
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 25 20980672
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 24 18981222
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 23 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 22 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 22 24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 20 18322460
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 20 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 19 24448447
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 18 18981222
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 18 22110043
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 18 24448447
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 17 18193060
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 16 17095540
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 15 18193060
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 15 20980672
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 15 18981222
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 15 18193060
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 14 20980672
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 13 18193060
mRNP on AdML, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 12 17095540
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 12 17095540
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 12 12226669
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 12 24448447
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 11 12226669
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 11 18193060
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 10 18193060
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
mRNP on short 5' exon, AdML, H. sapiens, (Merz et al 2007) H. sapiens 9 17095540
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 9 22110043
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 8 18193060
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 8 18981222
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 8 16809785
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 7 22110043
mRNP unspliced control, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 3 18322460
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562
A complex on MINX-MS2, ATPgammaS block, glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562

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