Nomenclature

Gene Symbol
AQR (H. sapiens)
Other Gene Symbols
DKFZp686B23123, IBP160, KIAA0560, fSAP164
Full Name
aquarius homolog (mouse)
Other Names
KIAA0560, functional spliceosome-associated protein 164, intron-binding protein aquarius, intron-binding protein of 160 kDa

Other Resources

Entrez: Gene Info
9716
Uniprot: Protein Info
AQR_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
115065
PDB: Structures
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SpliProt3D: Structural Model
AQR

Gene Product Info

Molecular Weight (kD)
171.3
Domains
—
Motifs
—
Features
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Complex Association
B complex, Bact complex, C complex, P complex
Class / Family
PRP19 related
Notes
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Orthologs

Name Organism
cwf11 S. pombe
CG31368 D. melanogaster
Y80D3A.2 C. elegans
AQR G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
AQR RBM22 Y2H: Bait/Prey 0.53 22365833
AQR ZNF830 Y2H: Bait/Prey 1 22365833
AQR ZNF830 Pull-down — 22365833
AQR WDR83 Y2H: Bait/Prey 0.67 22365833
AQR PQBP1 Y2H: Bait/Prey 0.33 22365833
AQR RBM4 Y2H: Bait/Prey 0.67 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 356 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 318 20980672
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 307 27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 284 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 219 20980672
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 203 18322460
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 163 18322460
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 158 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 156 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 153 18322460
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 131 24448447
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 102 18981222
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 97 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 97 21536652
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 91 27377154
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 73 19761775
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 66 27377154
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 65 18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 63 18981222
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 61 23345524
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 53 23345524
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 52 21526149
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 44 18322460
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 41 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 41 24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 39 16809785
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 36 11991638
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 35 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 32 24448447
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 30 18981222
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 30 21536652
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 25 17537823
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 25 27377154
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 24 19761775
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 24 18981222
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 20 17537823
CACN-1 pulldown with FLAG-HA tandem affinity from C. elegans, C. elegans, (Doherty et al 2014) C. elegans 18 24948787
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 14 12226669
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 13 12226669
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 11 18981222
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 9 27377154
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 8 16809785
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 5 21526149
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931

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