Nomenclature

Gene Symbol
HNRNPA1 (H. sapiens)
Other Gene Symbols
HNRPA1, HNRPA1L3, MGC102835, hnRNP A1, hnRNP-A1
Full Name
heterogeneous nuclear ribonucleoprotein A1
Other Names
hnRNP A1, Putative heterogeneous nuclear ribonucleoprotein A1-like 3, helix-destabilizing protein, heterogeneous nuclear ribonucleoprotein A1, heterogeneous nuclear ribonucleoprotein A1B protein, heterogeneous nuclear ribonucleoprotein B2 protein

Other Resources

Entrez: Gene Info
3178
Uniprot: Protein Info
ROA1_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
109420
PDB: Structures
1HA1, 1L3K, 1PGZ, 1PO6, 1U1K
SpliProt3D: Structural Model
HNRNPA1

Gene Product Info

Molecular Weight (kD)
38.7
Domains
RRM
Motifs
—
Features
—
Complex Association
A complex
Class / Family
hnRNP
Notes
—

Orthologs

Name Organism
Hrb87F D. melanogaster
Hrb98DE D. melanogaster
HNRNPA3 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
HNRNPA1 PPIL1 Y2H: Prey/Bait 0.5 22365833
HNRNPA1 TRA2B Y2H: Prey/Bait 0.88 22365833
HNRNPA1 HNRNPA1 Dervied from Literature — 10772858
HNRNPA1 HNRNPH3 Y2H: Prey/Bait 1 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 170 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 77 27377154
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 66 21536652
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 50 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 43 27377154
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 38 16809785
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 34 27377154
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 31 18193060
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 27 16809785
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 26 17537823
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 24 16809785
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 23 18193060
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 23 27377154
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 22 21536652
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 21 18193060
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 21 18193060
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 20 17332742
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 19 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 17 24448447
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 16 18193060
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 16 18981222
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 16 16809785
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 11 17537823
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 11 18322460
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 11 18981222
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 10 19761775
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 10 18193060
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 8 17095540
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 8 18193060
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 8 23345524
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 8 27377154
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 7 20980672
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 7 17537823
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 7 21536652
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 7 23345524
mRNP on AdML, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 6 17095540
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 6 17095540
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 5 11991638
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 5 21526149
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 3 19761775
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 3 20980672
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 3 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 3 20980672
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 3 11991638
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 1 18322460
mRNP unspliced control, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 1 18322460
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 1 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 1 24448447
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens ■ 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934

©2011 Spliceosome Component Database  All Rights Reserved.
design by juricalab