Nomenclature

Gene Symbol
SART1 (H. sapiens)
Other Gene Symbols
Ara1, HOMS1, MGC2038, SART1259, SNRNP110
Full Name
squamous cell carcinoma antigen recognized by T cells
Other Names
SART1, IgE autoantigen, SART-1, SART1(259) protein, SART1(800) protein, SNU66 homolog

Other Resources

Entrez: Gene Info
9092
Uniprot: Protein Info
SNUT1_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
114546
PDB: Structures
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SpliProt3D: Structural Model
SART1

Gene Product Info

Molecular Weight (kD)
90.3
Domains
—
Motifs
—
Features
—
Complex Association
B complex, tri-snRNP
Class / Family
tri-snRNP
Notes
—

Orthologs

Name Organism
SNU66 S. cerevisiae
snu66 S. pombe
CG6686 D. melanogaster
F19F10.9 C. elegans

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SART1 CHERP Y2H: Prey/Bait 0.94 22365833
SART1 RBM25 Y2H: Prey/Bait 0.5 22365833
SART1 SNRNP200 Dervied from Literature — 16723661
SART1 PRPF6 Dervied from Literature — 16723661
SART1 PRPF3 Dervied from Literature — 16723661
SART1 SART1 Dervied from Literature — 16723661
SART1 SNW1 Y2H: Bait/Prey 0.5 22365833
SART1 SNW1 Pull-down — 22365833
SART1 MFAP1 Y2H: Prey/Bait 0.5 22365833
SART1 SRSF4 Y2H: Prey/Bait 0.88 22365833
SART1 UBL5 Dervied from Literature — 15620657
SART1 UBL5 Y2H: Prey/Bait 1 22365833
SART1 ZCCHC10 Y2H: Prey/Bait 1 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 395 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 365 27377154
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 125 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 115 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 101 27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 73 27377154
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 71 21536652
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 65 18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 64 16809785
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 57 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 56 24448447
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 49 21536652
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 48 24448447
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 39 19941820
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 37 18981222
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 34 16809785
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 33 16809785
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 31 18981222
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 29 16809785
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 19 18981222
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 15 11804584
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 14 19941820
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 14 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 13 20980672
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 12 17537823
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 12 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 12 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 12 18981222
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 11 18322460
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 11 12226669
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 11 18981222
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 11 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 9 21536652
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 8 18193060
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 7 20980672
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 4 12226669
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 4 11991638
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 3 21536652
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 2 17537823
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 1 19935684
tri-snRNP, S. cerevisiae, (Stevens et al 1999) S. cerevisiae ■ 11720284
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae ■ 10449419
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
tri-snRNP, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe ■ 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562

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