Nomenclature

Gene Symbol
CHERP (H. sapiens)
Other Gene Symbols
DAN16, SCAF6, SRA1
Full Name
calcium homeostasis endoplasmic reticulum protein
Other Names
CHERP, ERPROT 213-21, ERPROT213-21, SR-related CTD associated factor 6, SR-related CTD-associated factor 6, calcium homeostasis endoplasmic reticulum protein

Other Resources

Entrez: Gene Info
10523
Uniprot: Protein Info
CHERP_HUMAN
Organism-Specific Database
BioGrid: Interaction Info
115778
PDB: Structures
SpliProt3D: Structural Model
CHERP

Gene Product Info

Molecular Weight (kD)
103.7
Domains
CID, G-patch
Motifs
Features
Complex Association
A complex
Class / Family
17S U2 snRNP associated
Notes

Orthologs

Name Organism
scaf6 D. melanogaster
F58G11.5 C. elegans
CHERP G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
CHERP SNRNP70 Y2H: Bidirectional 0.81 22365833
CHERP SF3B4 Y2H: Prey/Bait 1 22365833
CHERP U2AF1 Y2H: Bidirectional 1 22365833
CHERP U2AF2 Pull-down 22365833
CHERP U2AF2 Y2H: Prey/Bait 1 22365833
CHERP PRPF40A Y2H: Bidirectional 0.88 22365833
CHERP SART1 Y2H: Bait/Prey 0.94 22365833
CHERP PRPF38A Y2H: Bidirectional 1 22365833
CHERP DHX8 Y2H: Bait/Prey 1 22365833
CHERP DHX8 Pull-down 22365833
CHERP SNIP1 Y2H: Bait/Prey 1 22365833
CHERP RNPS1 Y2H: Prey/Bait 0.75 22365833
CHERP CCAR1 Y2H: Bidirectional 0.88 22365833
CHERP GNB2L1 Y2H: Prey/Bait 1 22365833
CHERP RBM7 Y2H: Prey/Bait 0.5 22365833
CHERP RBM39 Y2H: Bait/Prey 0.5 22365833
CHERP ARGLU1 Y2H: Bidirectional 0.7 22365833
CHERP HNRNPH3 Y2H: Prey/Bait 1 22365833
CHERP SNRNP27 Y2H: Prey/Bait 1 22365833
CHERP SNRNP27 Pull-down 22365833
CHERP LUC7L Y2H: Prey/Bait 1 22365833
CHERP LUC7L Pull-down 22365833
CHERP TTC14 Y2H: Prey/Bait 0.5 22365833
CHERP FRA10AC1 Pull-down 22365833
CHERP FRA10AC1 Y2H: Bidirectional 0.81 22365833
CHERP AGGF1 Y2H: Bidirectional 0.81 22365833
CHERP PPIL4 Y2H: Prey/Bait 0.5 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 23 27377154
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 20 21536652
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 20 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 20 27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 16 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 14 22110043
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 7 21536652
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 3 17537823
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 1 23345524
U2 17S, H. sapiens, (Will et al 2002) H. sapiens 12234937
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens 12477934
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 24448447

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