Nomenclature

Gene Symbol
RNPS1 (H. sapiens)
Other Gene Symbols
E5.1, MGC117332
Full Name
RNA binding protein S1, serine-rich domain
Other Names
RNPS1, RNA-binding protein S1, serine-rich domain, RNA-binding protein with serine-rich domain 1, SR protein, SR-related protein LDC2

Other Resources

Entrez: Gene Info
10921
Uniprot: Protein Info
RNPS1_HUMAN
Organism-Specific Database
BioGrid: Interaction Info
116125
PDB: Structures
4A8X
SpliProt3D: Structural Model
RNPS1

Gene Product Info

Molecular Weight (kD)
34.2
Domains
RRM
Motifs
Features
Class / Family
EJC/mRNP
Notes

Orthologs

Name Organism
RnpS1 D. melanogaster
K02F3.11 C. elegans
RNPS1 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
RNPS1 U2AF1 Y2H: Bait/Prey 1 22365833
RNPS1 CHERP Y2H: Bait/Prey 0.75 22365833
RNPS1 PRPF38A Y2H: Bidirectional 0.75 22365833
RNPS1 RBM8A Dervied from Literature 11707413
RNPS1 SRSF1 Y2H: Bidirectional 0.55 22365833
RNPS1 SRSF4 Y2H: Bait/Prey 0.75 22365833
RNPS1 SRSF6 Dervied from Literature 16189514
RNPS1 TRA2B Dervied from Literature 14729963
RNPS1 ACIN1 Y2H: Prey/Bait 0.5 22365833
RNPS1 PNN Dervied from Literature 14517304, 14729963
RNPS1 CDK11A Dervied from Literature 9580558

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 12 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 7 24448447
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 6 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 2 27377154
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 1 18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 1 23345524
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 1 24448447
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 1 27377154

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