Nomenclature

Gene Symbol
PNN (H. sapiens)
Other Gene Symbols
DRS, DRSP, SDK3, memA
Full Name
pinin, desmosome associated protein
Other Names
Pinin, 140 kDa nuclear and cell adhesion-related phosphoprotein, SR-like protein, desmosome-associated protein, domain-rich serine protein, melanoma metastasis clone A protein

Other Resources

Entrez: Gene Info
5411
Uniprot: Protein Info
PININ_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
111412
PDB: Structures
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SpliProt3D: Structural Model
PNN

Gene Product Info

Molecular Weight (kD)
81.6
Domains
—
Motifs
—
Features
—
Class / Family
EJC/mRNP
Notes
—

Orthologs

Name Organism
Pnn D. melanogaster
R186.7 C. elegans
PNN G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
PNN PRPF4B Dervied from Literature — 12077342
PNN PPIG Dervied from Literature — 15358154
PNN RNPS1 Dervied from Literature — 14517304, 14729963
PNN SRSF4 Dervied from Literature — 14578391
PNN SRRM2 Dervied from Literature — 14578391
PNN PNN Dervied from Literature — 16169070
PNN TOE1 Dervied from Literature — 16169070

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 23 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 18 20980672
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 14 17537823
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 11 18322460
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 10 17095540
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 10 17537823
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 9 24448447
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 7 11991638
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 6 17095540
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 6 27377154
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 4 17332742
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 4 23345524
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 3 18322460
SRM160 pulldown with BIC8 antibody, H. sapiens, (McCracken et al 2005) H. sapiens 3 16159877
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
SRM300 pulldown with Srm300 antibody, H. sapiens, (McCracken et al 2005) H. sapiens 2 16159877
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 1 11991638
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 1 23345524
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573

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