Nomenclature

Gene Symbol
PRPF4B (H. sapiens)
Other Gene Symbols
KIAA0536, PR4H, PRP4, PRP4H, PRP4K
Full Name
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Other Names
HPRP4 kinase, PRP4 kinase, PRP4 pre-mRNA-processing factor 4 homolog, dJ1013A10.1 (PRP4 protein kinase homolog), protein-serine/threonine kinase, serine/threonine-protein kinase PRP4 homolog

Other Resources

Entrez: Gene Info
8899
Uniprot: Protein Info
PRP4B_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
114416
PDB: Structures
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SpliProt3D: Structural Model
PRPF4B

Gene Product Info

Molecular Weight (kD)
117.0
Domains
Protein kinase
Motifs
—
Features
—
Class / Family
Recruited at B complex
Notes
—

Orthologs

Name Organism
prp4 S. pombe
CG7028 D. melanogaster
F22D6.5 C. elegans
PRPF4B G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
PRPF4B PRPF4B Dervied from Literature — 17513757
PRPF4B PNN Dervied from Literature — 12077342

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 185 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 86 27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 66 27377154
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 65 27377154
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 43 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 42 24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 40 27377154
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 36 20980672
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 34 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 34 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 33 18322460
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 28 27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 21 20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 19 18322460
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 18 18981222
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 13 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 11 20980672
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 10 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 10 18981222
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 8 17537823
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 7 21536652
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 6 17537823
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 6 24448447
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 4 21536652
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 2 21536652
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931

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