Nomenclature

Gene Symbol
smd1 (S. pombe)
Other Gene Symbols
—
Full Name
Sm snRNP core protein Smd1
Other Names
—, SPAC27D7.07c

Other Resources

Entrez: Gene Info
2542690
Uniprot: Protein Info
SMD1_SCHPO
Organism-Specific Database
—
BioGrid: Interaction Info
279143
PDB: Structures
—
SpliProt3D: Structural Model
—

Gene Product Info

Molecular Weight (kD)
13.1
Domains
—
Motifs
—
Features
—
Complex Association
17S U2 snRNP, A complex, B complex, Bact complex, C complex, P complex, tri-snRNP, U1 snRNP, U4/U6 snRNP, U5 snRNP
Class / Family
Sm
Notes
—

Orthologs

Name Organism
SNRPD1 H. sapiens
SMD1 S. cerevisiae
SmD1 D. melanogaster
T28D9.10 C. elegans
SNRPD1 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 325 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 296 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 264 21536652
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 225 21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 214 21536652
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 150 21386897
U1 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 145 21536652
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 133 21386897
17S U2 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 123 21536652
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 94 21386897
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 62 27377154
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 48 16809785
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 42 19935684
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 38 27377154
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 26 19935684
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 26 19935684
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 25 23431055
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 22 18322460
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 22 19941820
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 21 24448447
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 20 20980672
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 20 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 20 24448447
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 19 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 19 19935684
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 18 18322460
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 18 16809785
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 18 27377154
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 17 23431055
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 17 27377154
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 16 19935684
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 15 20980672
Dre4 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 15 21386897
Saf3 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 15 21386897
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 15 24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 15 27377154
Prp8 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 14 19789211
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 14 23431055
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 13 19935684
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 13 23431055
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 12 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 12 19935684
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 12 23431055
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 11 16809785
Urn1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 11 21386897
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 11 23431055
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 10 19941820
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 10 19935684
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 10 23431055
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 9 18981222
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 9 20980672
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 9 23431055
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 9 23431055
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 9 24448447
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 8 11804584
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 7 18193060
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 6 19761775
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 5 19941820
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 5 19941820
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 4 11884590
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 4 19941820
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 4 12226669
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 4 11884590
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 4 17537823
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 4 17537823
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 3 19941820
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 3 19761775
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 3 20980672
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 3 11991638
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
Clf1p-pulldown, S. cerevisiae, (Wang et al 2003) S. cerevisiae 3 12509417
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 3 23345524
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 3 21526149
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
Cwc21 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 2 19789211
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 2 21526149
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 1 17332742
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
U11/U12 18S di-snRNP, H. sapiens, (Will et al 2004) H. sapiens ■ 15146077
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
tri-snRNP, S. cerevisiae, (Stevens et al 1999) S. cerevisiae ■ 11720284
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae ■ 10449419
A-like complex (A') Weri, H. sapiens, (Sharma et al 2008) H. sapiens ■ 18193060
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
U1 snRNP, S. pombe, (Newo et al 2007) S. pombe ■ 17264129
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
CDC5L pulldown, H. sapiens, (Ajuh et al 1999) H. sapiens ■ 11101529
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe ■ 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, without splicing substrate, 250 mM salt wash, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, 250 mM salt wash, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

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