Nomenclature

Gene Symbol
CEF1 (S. cerevisiae)
Other Gene Symbols
NTC85
Full Name
Cef1p
Other Names
CEF1, YMR213W

Other Resources

Entrez: Gene Info
855253
Uniprot: Protein Info
CEF1_YEAST
Organism-Specific Database
S000004826
BioGrid: Interaction Info
35391
PDB: Structures
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SpliProt3D: Structural Model
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Gene Product Info

Molecular Weight (kD)
67.7
Domains
HTH myb-type
Motifs
—
Features
—
Complex Association
B complex, Bact complex, C complex, P complex
Class / Family
PRP19 complex
Notes
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Orthologs

Name Organism
CDC5L H. sapiens
cdc5 S. pombe
CG6905 D. melanogaster
D1081.8 C. elegans
CDC5L G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 1371 21386897
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 849 21386897
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 844 21386897
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 336 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 266 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 240 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 240 20980672
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 189 27377154
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 135 23431055
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 131 19935684
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 126 21536652
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 126 24448447
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 124 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 123 19935684
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 118 18322460
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 115 19935684
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 110 21536652
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 109 18322460
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 107 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 103 24448447
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 100 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 94 19935684
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 87 19941820
Urn1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 80 21386897
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 77 19935684
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 74 19935684
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 72 19941820
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 72 19935684
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 70 18322460
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 69 19941820
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 66 19935684
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 66 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 63 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 53 18322460
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 53 23431055
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 52 23431055
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 52 24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 50 16809785
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 49 24448447
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 48 16809785
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 48 23431055
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 47 23345524
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 46 18981222
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 44 23431055
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 43 16809785
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 43 23431055
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 42 19761775
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 42 23345524
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 42 23431055
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 38 23431055
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 38 23431055
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 36 20089683
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 36 23431055
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 35 11884590
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 35 21536652
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 33 16809785
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 32 20089683
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 28 18981222
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 27 27377154
Clf1p-pulldown, S. cerevisiae, (Wang et al 2003) S. cerevisiae 26 12509417
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 24 17537823
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 24 19941820
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 24 18981222
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 21 19941820
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 21 18981222
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 20 18981222
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 20 12226669
Prp43 dissasociated ILS 1-2 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 20 23431055
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 19 18322460
U2/U5/U6 complex Cwc1-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 19 11884590
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 19 18981222
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 18 19941820
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 18 11991638
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 18 18981222
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 18 27377154
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 16 11884590
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 16 18981222
U2/U5/U6 complex Snt309-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 14 11884590
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 14 19761775
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 14 20089683
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 13 11884590
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 12 12226669
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 11 11884590
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 11 17537823
Saf1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 9 21386897
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 9 21526149
CACN-1 pulldown with FLAG-HA tandem affinity from C. elegans, C. elegans, (Doherty et al 2014) C. elegans 9 24948787
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 7 11804584
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 7 18981222
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 7 21526149
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 6 11991638
Dre4 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 5 21386897
Cwc21 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 4 19789211
SKIP GST-tag pulldown, H. sapiens, (Zhang et al 2003) H. sapiens 3 12840015
Prp8 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 3 19789211
SRM160 pulldown with BIC8 antibody, H. sapiens, (McCracken et al 2005) H. sapiens 3 16159877
SRM300 pulldown with Srm300 antibody, H. sapiens, (McCracken et al 2005) H. sapiens 3 16159877
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 2 17332742
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 2 21536652
SRM160 pulldown with Srm160 antibody, H. sapiens, (McCracken et al 2005) H. sapiens 2 16159877
Released with ILS, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens ■ 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
CDC5L pulldown, H. sapiens, (Ajuh et al 1999) H. sapiens ■ 11101529

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