Nomenclature

Gene Symbol
RBMX2 (H. sapiens)
Other Gene Symbols
CGI-79
Full Name
RNA binding motif protein, X-linked 2
Other Names
RBMX2 , RNA-binding motif protein, X-linked 2

Other Resources

Entrez: Gene Info
51634
Uniprot: Protein Info
RBMX2_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
119648
PDB: Structures
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SpliProt3D: Structural Model
RBMX2

Gene Product Info

Molecular Weight (kD)
37.3
Domains
RRM
Motifs
—
Features
—
Complex Association
Bact complex, C complex
Class / Family
RES complex
Notes
—

Orthologs

Name Organism
IST3 S. cerevisiae
cwf29 S. pombe
CG10466 D. melanogaster
C30B5.4 C. elegans

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
RBMX2 PRPF40A Y2H: Bait/Prey 0.67 22365833
RBMX2 DHX8 Y2H: Bait/Prey 0.67 22365833
RBMX2 BUD13 Y2H: Bait/Prey 1 22365833
RBMX2 BUD13 Pull-down — 22365833
RBMX2 NKAP Pull-down — 22365833
RBMX2 NKAP Y2H: Bidirectional 1 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Released with ILS, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 25 23431055
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 19 19935684
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 18 23431055
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 16 19935684
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 16 23431055
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 16 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 13 18322460
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 13 18322460
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 12 19941820
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 10 19935684
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 9 20980672
Dre4 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 9 21386897
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 9 23345524
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 9 23431055
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 8 23431055
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 7 11804584
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 6 18322460
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 6 24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 5 23345524
Released from Post-catalytic complex, deltaPrp22, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 5 23431055
Prp43 dissasociated ILS 1-2 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 5 23431055
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 5 23431055
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 4 11884590
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 4 18981222
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 4 19935684
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 3 19941820
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 3 20089683
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 3 19941820
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 2 19941820
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 2 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 2 27377154
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 1 11884590
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 1 19935684
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684

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