Nomenclature

Gene Symbol
BUD13 (H. sapiens)
Other Gene Symbols
Cwc26, FLJ27090, MGC13125, fSAP71
Full Name
BUD13 homolog (S. cerevisiae)
Other Names
MGC13125, BUD13 homolog, functional spliceosome-associated protein 71

Other Resources

Entrez: Gene Info
84811
Uniprot: Protein Info
BUD13_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
124272
PDB: Structures
—
SpliProt3D: Structural Model
BUD13

Gene Product Info

Molecular Weight (kD)
70.5
Domains
—
Motifs
—
Features
—
Complex Association
Bact complex, C complex, P complex
Class / Family
RES complex
Notes
—

Orthologs

Name Organism
BUD13 S. cerevisiae
cwf26 S. pombe
CG13625 D. melanogaster
R08D7.1 C. elegans
BUD13 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
BUD13 GPKOW Pull-down — 22365833
BUD13 GPKOW Y2H: Bidirectional 1 22365833
BUD13 RBMX2 Y2H: Prey/Bait 1 22365833
BUD13 RBMX2 Pull-down — 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 108 20980672
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 81 19941820
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 78 20980672
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 63 23431055
Prp43 dissasociated ILS 1-2 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 62 23431055
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 58 19935684
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 58 23431055
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 56 27377154
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 45 19935684
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 44 18322460
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 38 18322460
Released with ILS, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 37 23431055
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 33 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 33 19935684
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 30 19941820
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 29 19935684
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 26 19941820
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 25 27377154
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 23 19941820
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 23 20980672
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 23 19935684
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 22 21536652
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 21 20980672
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 19 19935684
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 19 24448447
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 19 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 17 18322460
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 17 23431055
Released from Post-catalytic complex, deltaPrp22, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 17 23431055
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 17 23431055
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 17 24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 16 18322460
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 16 21536652
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 16 24448447
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 14 20089683
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 13 16809785
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 13 24448447
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 11 19941820
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 11 19935684
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 10 23431055
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 8 23345524
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 7 12226669
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 6 16809785
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 6 23431055
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 5 23431055
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 4 19941820
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 4 23345524
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 3 18981222
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 3 16809785
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 2 19761775
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 2 21536652
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 2 27377154
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 1 19761775
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931

©2011 Spliceosome Component Database  All Rights Reserved.
design by juricalab