Nomenclature

Gene Symbol
l(1)10Bb (D. melanogaster)
Other Gene Symbols
10Ba, CG1639, Dmel\CG1639, l(1)G0169, l(1)G14
Full Name
lethal (1) 10Bb
Other Names
—, CG1639 gene product from transcript CG1639-RA

Other Resources

Entrez: Gene Info
32069
Uniprot: Protein Info
O97454_DROME
Organism-Specific Database
FBgn0001491
BioGrid: Interaction Info
58481
PDB: Structures
—
SpliProt3D: Structural Model
—

Gene Product Info

Molecular Weight (kD)
17.0
Domains
—
Motifs
—
Features
—
Complex Association
B complex, Bact complex, C complex, P complex
Class / Family
PRP19 related
Notes
—

Orthologs

Name Organism
BUD31 H. sapiens
BUD31 S. cerevisiae
cwf14 S. pombe
C07A9.2 C. elegans
PFE1140c P. falciparum
BUD31 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 277 21386897
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 211 21536652
Aim4 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 173 21386897
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 173 21386897
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 111 21536652
Urn1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 79 21386897
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 79 21386897
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 37 21536652
Prp43 dissasociated ILS 1-2 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 30 23431055
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 29 20980672
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 28 27377154
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 26 24448447
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 25 19935684
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 24 18322460
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 24 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 24 24448447
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 22 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 21 27377154
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 20 18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 20 16809785
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 20 19935684
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 16 23431055
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 14 20980672
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 14 19935684
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 14 19935684
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 13 19761775
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 13 20980672
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 13 23431055
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 13 24448447
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 12 19941820
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 12 18981222
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 12 19935684
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 12 23345524
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 11 19941820
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 11 19935684
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 11 23345524
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 10 23431055
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 10 23431055
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 9 20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 9 18981222
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 9 18981222
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 8 18981222
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 8 16809785
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 7 20089683
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 7 18981222
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 7 23431055
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 6 23431055
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 5 20089683
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 4 19941820
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 4 20089683
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 4 11884590
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 4 19935684
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 3 18322460
CACN-1 pulldown with FLAG-HA tandem affinity from C. elegans, C. elegans, (Doherty et al 2014) C. elegans 3 24948787
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 2 17537823
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 2 16809785
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 2 16809785
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 2 19935684
Released with ILS, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
U2/U5/U6 complex Snt309-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
U2/U5/U6 complex Cwc1-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
Cwc21 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 1 19789211
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 1 19935684
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 1 27377154
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
Clf1p-pulldown, S. cerevisiae, (Wang et al 2003) S. cerevisiae ■ 12509417
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684

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