Nomenclature

Gene Symbol
CDC40 (S. cerevisiae)
Other Gene Symbols
PRP17, SLT15, SLU4
Full Name
Cdc40p
Other Names
PRP17, YDR364C

Other Resources

Entrez: Gene Info
851968
Uniprot: Protein Info
PRP17_YEAST
Organism-Specific Database
S000002772
BioGrid: Interaction Info
32421
PDB: Structures
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SpliProt3D: Structural Model
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Gene Product Info

Molecular Weight (kD)
52.0
Domains
—
Motifs
—
Features
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Complex Association
Bact complex, C complex, P complex
Class / Family
Second step factors
Notes
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Orthologs

Name Organism
CDC40 H. sapiens
prp17 S. pombe
CG6015 D. melanogaster
F49D11.1 C. elegans
CDC40 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 901 21386897
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 696 21386897
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 636 21386897
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 147 20980672
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 142 21536652
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 140 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 110 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 105 20980672
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 92 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 85 27377154
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 73 18322460
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 63 19935684
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 60 23431055
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 53 18322460
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 52 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 47 24448447
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 44 24448447
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 41 23431055
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 39 19935684
Prp43 dissasociated ILS 1-2 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 39 23431055
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 36 19941820
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 35 18981222
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 35 23431055
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 33 23431055
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 33 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 33 27377154
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 31 19935684
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 30 19935684
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 30 23345524
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 28 23345524
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 26 11884590
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 26 23431055
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 24 19941820
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 24 11991638
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 24 21536652
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 23 19761775
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 23 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 22 19935684
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 21 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 20 24448447
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 19 18322460
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 19 23431055
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 18 18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 17 18981222
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 16 23431055
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 15 17537823
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 15 20089683
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 15 20089683
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 15 18981222
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 15 23431055
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 14 19941820
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 14 23431055
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 11 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 11 24448447
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 10 19941820
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 9 23431055
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 8 16809785
CACN-1 pulldown with FLAG-HA tandem affinity from C. elegans, C. elegans, (Doherty et al 2014) C. elegans 8 24948787
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 8 27377154
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 7 11884590
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 7 20089683
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 6 12226669
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
Saf1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 6 21386897
Released with ILS, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 6 23431055
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 6 27377154
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 5 11884590
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 5 19761775
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 5 18981222
U2/U5/U6 complex Snt309-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 3 11884590
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 3 21526149
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 2 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 2 21526149
U2/U5/U6 complex Cwc2-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
Cwc21 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 1 19789211
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684

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