Nomenclature

Gene Symbol
THOC5 (H. sapiens)
Other Gene Symbols
C22orf19, Fmip, PK1.3, fSAP79
Full Name
THO complex 5
Other Names
KIAA0983, Fms-interacting protein, NF2/meningioma region protein pK1.3, PP39.2, THO complex subunit 5 homolog, functional spliceosome-associated protein 79

Other Resources

Entrez: Gene Info
8563
Uniprot: Protein Info
THOC5_HUMAN
Organism-Specific Database
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BioGrid: Interaction Info
114132
PDB: Structures
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SpliProt3D: Structural Model
THOC5

Gene Product Info

Molecular Weight (kD)
78.5
Domains
—
Motifs
Nuclear localization signal
Features
—
Class / Family
TREX
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
THOC5 LSM3 Y2H: Prey/Bait 0.75 22365833
THOC5 PPIL1 Y2H: Prey/Bait 0.5 22365833
THOC5 ZNF830 Y2H: Prey/Bait 0.75 22365833
THOC5 THOC1 Dervied from Literature — 19059247
THOC5 THOC1 Y2H: Prey/Bait 0.5 22365833
THOC5 THOC7 Dervied from Literature — 19059247

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 16 24448447
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 13 24448447
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 8 18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 8 20980672
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 7 12226669
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 7 21536652
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 7 24448447
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 6 24448447
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 5 17537823
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 4 20980672
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 3 17095540
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 3 20980672
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 2 17537823
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931

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