Nomenclature

Gene Symbol
CWC27 (H. sapiens)
Other Gene Symbols
NY-CO-10, SDCCAG10
Full Name
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
Other Names
antigen NY-CO-10 putatuve nuclear, PPIase CWC27, PPIase SDCCAG10, antigen NY-CO-10, peptidyl-prolyl cis-trans isomerase CWC27 homolog, peptidyl-prolyl cis-trans isomerase SDCCAG10

Other Resources

Entrez: Gene Info
10283
Uniprot: Protein Info
CWC27_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
115572
PDB: Structures
2HQ6
SpliProt3D: Structural Model
SDCCAG10

Gene Product Info

Molecular Weight (kD)
53.8
Domains
PPIase cyclophilin-type
Motifs
—
Features
—
Complex Association
Bact complex, C complex, P complex
Class / Family
Recruited at Bact complex
Notes
—

Orthologs

Name Organism
CWC27 S. cerevisiae
cyp7 S. pombe
CG10907 D. melanogaster
Y17G7B.9 C. elegans
CWC27 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 190 21536652
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 62 19935684
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 58 20980672
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 54 20980672
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 53 21536652
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 32 19935684
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 29 19941820
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 26 19935684
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 26 21536652
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 20 19935684
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 19 20980672
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 15 23431055
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 13 18322460
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 13 24448447
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 12 20089683
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 12 23431055
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 11 19941820
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 11 20980672
Prp43 dissasociated ILS 1-2 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 11 23431055
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 9 19935684
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 8 18322460
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 6 19941820
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 6 11884590
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 6 23345524
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 6 23431055
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 6 24448447
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 5 11991638
U2/U5/U6 complex Prp19-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 4 11884590
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 4 17537823
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
Prp43 dissasociated ILS 7-8 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 4 23431055
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 4 24448447
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Released with ILS, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 2 19761775
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 2 18322460
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 2 19941820
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684

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