Nomenclature

Gene Symbol
DDX39B (H. sapiens)
Other Gene Symbols
BAT1, D6S81E, UAP56
Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Other Names
—, 56 kDa U2AF65-associated protein, ATP-dependent RNA helicase p47, HLA-B-associated transcript 1 protein, nuclear RNA helicase (DEAD family), spliceosome RNA helicase BAT1

Other Resources

Entrez: Gene Info
7919
Uniprot: Protein Info
DX39B_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
113649
PDB: Structures
1T5I, 1T6N, 1XTI, 1XTJ, 1XTK
SpliProt3D: Structural Model
BAT1

Gene Product Info

Molecular Weight (kD)
49.0
Domains
Helicase ATP-binding, Helicase C-terminal
Motifs
DECD box, Q motif
Features
—
Class / Family
other rna binding domain containing
Notes
—

Orthologs

Name Organism
SUB2 S. cerevisiae
uap56 S. pombe
Hel25E D. melanogaster
PFB0445c P. falciparum

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
DDX39B U2AF2 Dervied from Literature — 9242493
DDX39B ALYREF Dervied from Literature — 14667819, 15047853
DDX39B RBM39 Dervied from Literature — 14667819
DDX39B DDX39B Dervied from Literature — 14667819

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 21 18322460
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 21 27377154
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 18 24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 16 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 15 27377154
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 12 17537823
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 12 17537823
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 11 20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 11 18322460
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 11 27377154
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 9 24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 8 27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 6 20980672
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 6 24448447
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 6 27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 5 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 4 22110043
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 3 20089683
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 2 18981222
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

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