Nomenclature

Gene Symbol
HNRNPK (H. sapiens)
Other Gene Symbols
CSBP, FLJ41122, HNRPK, TUNP
Full Name
heterogeneous nuclear ribonucleoprotein K
Other Names
hnRNP K, dC-stretch binding protein, heterogeneous nuclear ribonucleoprotein K, transformation upregulated nuclear protein

Other Resources

Entrez: Gene Info
3190
Uniprot: Protein Info
HNRPK_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
109431
PDB: Structures
1J5K, 1KHM, 1ZZI, 1ZZJ, 1ZZK
SpliProt3D: Structural Model
HNRNPK

Gene Product Info

Molecular Weight (kD)
51.0
Domains
KH
Motifs
—
Features
—
Class / Family
hnRNP
Notes
—

Orthologs

Name Organism
F26B1.2 C. elegans
HNRNPK G. gallus
HNRPK G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
HNRNPK SNRPA Y2H: Bidirectional 0.84 22365833
HNRNPK U2AF2 Y2H: Prey/Bait 0.62 22365833
HNRNPK SF1 Y2H: Bidirectional 0.73 22365833
HNRNPK CTNNBL1 Y2H: Prey/Bait 0.5 22365833
HNRNPK SRSF7 Dervied from Literature — 10809782
HNRNPK RBFOX2 Y2H: Bidirectional 0.85 22365833
HNRNPK SRRT Y2H: Prey/Bait 0.5 22365833
HNRNPK CCAR1 Y2H: Bidirectional 0.8 22365833
HNRNPK DHX9 Y2H: Prey/Bait 0.5 22365833
HNRNPK CIRBP Y2H: Bidirectional 0.85 22365833
HNRNPK RBM42 Dervied from Literature — 16189514
HNRNPK RBM42 Y2H: Bidirectional 0.7 22365833
HNRNPK RBM10 Y2H: Bait/Prey 0.88 22365833
HNRNPK SRSF3 Dervied from Literature — 10809782
HNRNPK RBM7 Dervied from Literature — 16189514
HNRNPK PABPC1 Y2H: Prey/Bait 0.4 22365833
HNRNPK DDX17 Y2H: Bidirectional 0.7 22365833
HNRNPK PTBP1 Dervied from Literature — 10772858
HNRNPK ELAVL1 Y2H: Bait/Prey 0.4 22365833
HNRNPK MATR3 Dervied from Literature — 16189514
HNRNPK YBX1 Dervied from Literature — 10809782
HNRNPK HNRNPA0 Y2H: Bait/Prey 0.6 22365833
HNRNPK PCBP2 Dervied from Literature — 10772858
HNRNPK PCBP1 Dervied from Literature — 16713569
HNRNPK HNRNPD Y2H: Bait/Prey 0.96 22365833
HNRNPK RBMX Y2H: Bait/Prey 0.8 22365833
HNRNPK RBMX Dervied from Literature — 10749975, 16189514
HNRNPK HNRNPK Y2H: Homodimer 0.4 22365833
HNRNPK HNRNPK Dervied from Literature — 16189514
HNRNPK RALY Y2H: Bidirectional 0.81 22365833
HNRNPK SYNCRIP Y2H: Bait/Prey 0.87 22365833
HNRNPK DDX5 Y2H: Bidirectional 0.88 22365833
HNRNPK KHDRBS1 Y2H: Bait/Prey 0.4 22365833
HNRNPK RBM4 Y2H: Bait/Prey 0.6 22365833
HNRNPK QKI Dervied from Literature — 16189514, 16713569
HNRNPK KHDRBS1 Dervied from Literature — 12370808
HNRNPK KHDRBS3 Dervied from Literature — 16189514
HNRNPK KHDRBS3 Y2H: Bidirectional 0.6 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 18 17537823
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 18 17537823
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 18 18193060
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 17 18322460
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 12 18322460
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 12 24448447
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 12 24448447
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 11 18193060
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 10 18193060
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 7 18193060
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 3 18981222
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 3 11991638
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 1 18322460
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 1 27377154
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447

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