Nomenclature

Gene Symbol
SYNCRIP (H. sapiens)
Other Gene Symbols
FLJ31626, GRY-RBP, GRYRBP, HNRPQ1, NSAP1
Full Name
synaptotagmin binding, cytoplasmic RNA interacting protein
Other Names
Gry-Rbp, NS1-associated protein 1, glycine- and tyrosine-rich RNA-binding protein, heterogeneous nuclear ribonucleoprotein Q

Other Resources

Entrez: Gene Info
10492
Uniprot: Protein Info
HNRPQ_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
115755
PDB: Structures
2DGU
SpliProt3D: Structural Model
SYNCRIP

Gene Product Info

Molecular Weight (kD)
69.6
Domains
RRM
Motifs
Bipartite nuclear localization signal
Features
—
Class / Family
hnRNP
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SYNCRIP HNRNPAB Dervied from Literature — 11352648
SYNCRIP HNRNPD Dervied from Literature — 12674497
SYNCRIP HNRNPK Y2H: Prey/Bait 0.87 22365833
SYNCRIP HNRNPU Y2H: Prey/Bait 0.75 22365833
SYNCRIP SYNCRIP Dervied from Literature — 15479637
SYNCRIP SMN1 Dervied from Literature — 11773003

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 49 27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 23 18981222
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 21 18193060
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 19 27377154
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 18 17537823
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 18 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 15 18322460
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 15 18193060
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 14 21536652
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 14 22110043
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 13 18981222
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 12 18193060
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 12 18193060
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 12 24448447
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 7 18193060
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 6 18322460
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 6 22110043
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 6 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 4 17332742
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 3 11991638
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 3 23345524
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 3 22110043
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 3 24448447
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
mRNP unspliced control, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 1 11991638
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 1 23345524
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens ■ 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669

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