Nomenclature

Gene Symbol
SRSF7 (H. sapiens)
Other Gene Symbols
9G8, AAG3, SFRS7
Full Name
serine/arginine-rich splicing factor 7
Other Names
9G8, SR splicing factor 7, aging-associated protein 3, serine/arginine-rich splicing factor 7, splicing factor 9G8, splicing factor, arginine/serine-rich 7, 35kDa

Other Resources

Entrez: Gene Info
6432
Uniprot: Protein Info
SRSF7_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
112330
PDB: Structures
2HVZ
SpliProt3D: Structural Model
SFRS7

Gene Product Info

Molecular Weight (kD)
27.4
Domains
RRM
Motifs
—
Features
—
Class / Family
SR protein
Notes
—

Orthologs

Name Organism
x16 D. melanogaster
C33H5.12 C. elegans

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SRSF7 PCBP2 Dervied from Literature — 8871564
SRSF7 HNRNPK Dervied from Literature — 10809782
SRSF7 RBBP6 Dervied from Literature — 18624398
SRSF7 CDK11A Dervied from Literature — 12501247

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 127 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 126 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 97 21536652
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 77 18322460
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 76 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 68 24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 61 18322460
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 57 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 54 24448447
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 48 24448447
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 39 18322460
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 28 20980672
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 28 27377154
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 27 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 27 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 26 20980672
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 24 16809785
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 23 24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 22 16809785
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 20 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 20 27377154
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 17 16809785
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 17 27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 15 18981222
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 15 17332742
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 13 16809785
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 13 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 9 27377154
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 6 17537823
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
mRNP on AdML, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 5 22110043
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 4 17095540
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 4 22110043
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 1 11991638
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
A-like complex (A') Weri, H. sapiens, (Sharma et al 2008) H. sapiens ■ 18193060
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562
A complex on MINX-MS2, ATPgammaS block, glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562

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