Nomenclature

Gene Symbol: CG7757 (D. melanogaster)
Other Gene Symbols: Dmel\CG7757, PRPF3, Prp3
Full Name: CG7757
Other Names: —, CG7757 gene product from transcript CG7757-RA

Other Resources

Entrez: Gene Info: 40172
Uniprot: Protein Info: Q8MRG6_DROME
Organism-Specific Database: FBgn0036915
BioGrid: Interaction Info: 65440
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 60.1
Domains: —
Motifs: —
Features: —
Complex Association: B complex, tri-snRNP, U4/U6 snRNP
Class / Family: U4/U6 snRNP
Notes: —

Orthologs

Name	Organism
PRPF3	H. sapiens
PRP3	S. cerevisiae
prp3	S. pombe
M03C11.7	C. elegans
PRPF3	G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	255	27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	186	27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	116	27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	97	27377154
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	85	16809785
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	85	27377154
tri-snRNP, H. sapiens, (Agafonov et al 2011)	H. sapiens	84	21536652
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	82	16809785
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	77	27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	75	18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	73	24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	67	18322460
B complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	63	18322460
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	49	24448447
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	43	16809785
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	41	18981222
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009)	H. sapiens	34	18981222
B complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	32	21536652
penta-snRNP, S. cerevisiae, (Stevens et al 2002)	S. cerevisiae	29	11804584
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009)	H. sapiens	27	18981222
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	27	19941820
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	20	16809785
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010)	H. sapiens	17	20980672
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	17	18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	15	18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	15	18981222
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	14	22110043
C complex on PM5, H. sapiens, (Bessonov et al 2010)	H. sapiens	13	20980672
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	13	17537823
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	12	18981222
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	12	24448447
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	11	19941820
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	11	18322460
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	9	12226669
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	8	17537823
A complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	8	21536652
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	5	12226669
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	5	18193060
Mixed complexes Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	3	18193060
C complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	3	18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	3	20980672
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	3	24448447
mRNP on short 5' exon, AdML, H. sapiens, (Merz et al 2007)	H. sapiens	2	17095540
C complex on PM5, H. sapiens, (Agafonov et al 2011)	H. sapiens	2	21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011)	H. sapiens	1	21536652
tri-snRNP, S. cerevisiae, (Stevens et al 1999)	S. cerevisiae	■	11720284
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999)	S. cerevisiae	■	10449419
tri-snRNP, H. sapiens, (Makarov et al 2002)	H. sapiens	■	12411573
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999)	H. sapiens	■	9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005)	S. pombe	■	15755920
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562