Nomenclature

Gene Symbol
CHERP (H. sapiens)
Other Gene Symbols
DAN16, SCAF6, SRA1
Full Name
calcium homeostasis endoplasmic reticulum protein
Other Names
CHERP, ERPROT 213-21, ERPROT213-21, SR-related CTD associated factor 6, SR-related CTD-associated factor 6, calcium homeostasis endoplasmic reticulum protein

Other Resources

Entrez: Gene Info
10523
Uniprot: Protein Info
CHERP_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
115778
PDB: Structures
—
SpliProt3D: Structural Model
CHERP

Gene Product Info

Molecular Weight (kD)
103.7
Domains
CID, G-patch
Motifs
—
Features
—
Complex Association
A complex
Class / Family
17S U2 snRNP associated
Notes
—

Orthologs

Name Organism
scaf6 D. melanogaster
F58G11.5 C. elegans
CHERP G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
CHERP SNRNP70 Y2H: Bidirectional 0.81 22365833
CHERP SF3B4 Y2H: Prey/Bait 1 22365833
CHERP U2AF1 Y2H: Bidirectional 1 22365833
CHERP U2AF2 Pull-down — 22365833
CHERP U2AF2 Y2H: Prey/Bait 1 22365833
CHERP PRPF40A Y2H: Bidirectional 0.88 22365833
CHERP SART1 Y2H: Bait/Prey 0.94 22365833
CHERP PRPF38A Y2H: Bidirectional 1 22365833
CHERP DHX8 Y2H: Bait/Prey 1 22365833
CHERP DHX8 Pull-down — 22365833
CHERP SNIP1 Y2H: Bait/Prey 1 22365833
CHERP RNPS1 Y2H: Prey/Bait 0.75 22365833
CHERP CCAR1 Y2H: Bidirectional 0.88 22365833
CHERP GNB2L1 Y2H: Prey/Bait 1 22365833
CHERP RBM7 Y2H: Prey/Bait 0.5 22365833
CHERP RBM39 Y2H: Bait/Prey 0.5 22365833
CHERP ARGLU1 Y2H: Bidirectional 0.7 22365833
CHERP HNRNPH3 Y2H: Prey/Bait 1 22365833
CHERP SNRNP27 Y2H: Prey/Bait 1 22365833
CHERP SNRNP27 Pull-down — 22365833
CHERP LUC7L Y2H: Prey/Bait 1 22365833
CHERP LUC7L Pull-down — 22365833
CHERP TTC14 Y2H: Prey/Bait 0.5 22365833
CHERP FRA10AC1 Pull-down — 22365833
CHERP FRA10AC1 Y2H: Bidirectional 0.81 22365833
CHERP AGGF1 Y2H: Bidirectional 0.81 22365833
CHERP PPIL4 Y2H: Prey/Bait 0.5 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 23 27377154
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 20 21536652
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 20 27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 20 27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 16 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 14 22110043
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 7 21536652
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 3 17537823
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 1 23345524
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens ■ 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447

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