Nomenclature

Gene Symbol
CELE_B0495.6 (C. elegans)
Other Gene Symbols
moa-2
Full Name
Protein MOA-2
Other Names
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Other Resources

Entrez: Gene Info
182004
Uniprot: Protein Info
YP66_CAEEL
Organism-Specific Database
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BioGrid: Interaction Info
46867
PDB: Structures
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SpliProt3D: Structural Model
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Gene Product Info

Molecular Weight (kD)
9.9
Domains
—
Motifs
—
Features
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Complex Association
17S U2 snRNP, A complex, B complex, Bact complex, C complex, P complex
Class / Family
17S U2 snRNP
Notes
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Orthologs

Name Organism
SF3B5 H. sapiens
YSF3 S. cerevisiae
splicing factor 3B S. pombe
CG11985 D. melanogaster
SF3B5 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
17S U2 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 104 21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 93 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 67 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 42 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 40 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 21 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 16 27377154
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 9 19941820
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 9 19935684
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 7 20980672
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 6 20980672
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 6 16809785
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 5 19935684
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 5 23345524
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 3 19941820
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 3 16809785
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 3 23345524
Prp43 dissasociated ILS 3-4 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae 2 20089683
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 2 19941820
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 2 18981222
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 2 17537823
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 2 16809785
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 1 18322460
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 1 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
SF3b, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
U11/U12 18S di-snRNP, H. sapiens, (Will et al 2004) H. sapiens ■ 15146077
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae ■ 19935684

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