Nomenclature

Gene Symbol: cdc28 (S. pombe)
Other Gene Symbols: —
Full Name: ATP-dependent RNA helicase Cdc28
Other Names: —, SPBC19C2.01

Other Resources

Entrez: Gene Info: 2540707
Uniprot: Protein Info: CDC28_SCHPO
Organism-Specific Database: —
BioGrid: Interaction Info: 277230
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 121.2
Domains: Helicase ATP-binding, Helicase C-terminal
Motifs: DEAH box
Features: —
Complex Association: Bact complex, C complex, P complex
Class / Family: Recruited at Bact complex
Notes: —

Orthologs

Name	Organism
DHX16	H. sapiens
PRP2	S. cerevisiae
l(2)37Cb	D. melanogaster
C04H5.6	C. elegans

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	157	20980672
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010)	H. sapiens	136	20980672
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	136	19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	136	19935684
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	116	19941820
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	107	19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	94	19935684
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	81	18322460
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	81	19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	78	19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	77	19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	73	19935684
C complex on PM5, H. sapiens, (Bessonov et al 2010)	H. sapiens	65	20980672
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	64	19941820
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010)	S. cerevisiae	59	20089683
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010)	H. sapiens	56	20980672
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011)	H. sapiens	51	21536652
B complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	38	18322460
C complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	35	18322460
C complex on PM5, H. sapiens, (Agafonov et al 2011)	H. sapiens	33	21536652
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	33	24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	27	18322460
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	24	19941820
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	20	24448447
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	19	19941820
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	17	24448447
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	14	24448447
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013)	H. sapiens	13	23345524
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	12	18322460
B complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	10	21536652
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	8	18981222
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	8	16809785
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	7	18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	7	18981222
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	6	12226669
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	6	18981222
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013)	H. sapiens	6	23345524
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	5	12226669
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	5	18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	5	18981222
C complex exons trimmed, H. sapiens, (Ilagan et al 2009)	H. sapiens	4	19761775
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009)	H. sapiens	3	18981222
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	3	16809785
C complex, H. sapiens, (Ilagan et al 2009)	H. sapiens	2	19761775
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	2	19935684
C complex, H. sapiens, (Jurica et al 2002)	H. sapiens	1	11991638
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006)	H. sapiens	■	17114945