Nomenclature

Gene Symbol
Y111B2A.18 (C. elegans)
Other Gene Symbols
Full Name
SR Protein (splicing factor) family member (rsp-3)
Other Names
—, Y111B2A.18

Other Resources

Entrez: Gene Info
176688
Uniprot: Protein Info
RSP3_CAEEL
Organism-Specific Database
WBGene00004700
PDB: Structures
SpliProt3D: Structural Model

Gene Product Info

Molecular Weight (kD)
28.7
Domains
RRM
Motifs
Features
Notes

Orthologs

Name Organism
SRSF1 H. sapiens
SF2 D. melanogaster
SRSF1 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 253 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 207 21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 107 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 100 21536652
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 89 17332742
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 77 18322460
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 68 16809785
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 55 16809785
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 42 20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 42 18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 37 16809785
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 32 18322460
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 32 24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 29 18322460
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 29 20980672
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 29 27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 28 20980672
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 28 24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 28 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 27 27377154
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 24 20980672
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 24 24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 24 27377154
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 21 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 18 18322460
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 18 16809785
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 18 24448447
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 15 18981222
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 15 27377154
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 12 12226669
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 12 18981222
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 11 12226669
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 10 22110043
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 9 18981222
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 8 18193060
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 8 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 8 18981222
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 7 18193060
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 7 18981222
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 7 22110043
mRNP on AdML, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 6 17095540
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
mRNP on short 5' exon, AdML, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 4 17537823
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 4 18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007) H. sapiens 3 17095540
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 3 17095540
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 3 17537823
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 1 11991638
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
U2 17S, H. sapiens, (Will et al 2002) H. sapiens 12234937
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens 12176931
CDC5L pulldown, H. sapiens, (Ajuh et al 1999) H. sapiens 11101529
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens 12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens 17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens 27411562
A complex on MINX-MS2, ATPgammaS block, glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens 27411562

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