Nomenclature

Gene Symbol: SRSF1 (G. gallus)
Other Gene Symbols: SFRS1
Full Name: serine/arginine-rich splicing factor 1
Other Names: —, serine/arginine-rich splicing factor 1, splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor)

Other Resources

Entrez: Gene Info: 772264
Uniprot: Protein Info: SRSF1_CHICK
Organism-Specific Database: —
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 28.1
Domains: RRM
Motifs: —
Features: —
Notes: —

Orthologs

Name	Organism
SRSF1	H. sapiens
SF2	D. melanogaster
Y111B2A.18	C. elegans

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	253	21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011)	H. sapiens	207	21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	107	21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011)	H. sapiens	100	21536652
A complex, H. sapiens, (Behzadnia et al 2007)	H. sapiens	89	17332742
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	77	18322460
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	68	16809785
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	55	16809785
C complex on PM5, H. sapiens, (Bessonov et al 2010)	H. sapiens	42	20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	42	18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	37	16809785
C complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	32	18322460
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	32	24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	29	18322460
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010)	H. sapiens	29	20980672
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	29	27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010)	H. sapiens	28	20980672
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	28	24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	28	27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	27	27377154
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	24	20980672
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	24	24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	24	27377154
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	21	27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	18	18322460
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	18	16809785
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	18	24448447
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009)	H. sapiens	15	18981222
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	15	27377154
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	12	12226669
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	12	18981222
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	11	12226669
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	10	22110043
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	9	18981222
EDC-A complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	8	18193060
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	8	18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	8	18981222
Mixed complexes Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	7	18193060
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	7	18981222
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011)	H. sapiens	7	22110043
mRNP on AdML, heparin treated, H. sapiens, (Merz et al 2007)	H. sapiens	6	17095540
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	6	18193060
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	6	18981222
mRNP on short 5' exon, AdML, H. sapiens, (Merz et al 2007)	H. sapiens	5	17095540
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	4	17537823
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009)	H. sapiens	4	18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	4	18981222
mRNP on BetaGlobin, heparin treated, H. sapiens, (Merz et al 2007)	H. sapiens	3	17095540
mRNP on AdML, H. sapiens, (Merz et al 2007)	H. sapiens	3	17095540
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	3	17537823
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007)	H. sapiens	1	17095540
C complex, H. sapiens, (Jurica et al 2002)	H. sapiens	1	11991638
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	1	22110043
U2 17S, H. sapiens, (Will et al 2002)	H. sapiens	■	12234937
E complex Weri, H. sapiens, (Sharma et al 2005)	H. sapiens	■	16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
CDC5L pulldown, H. sapiens, (Ajuh et al 1999)	H. sapiens	■	11101529
A complex, H. sapiens, (Hartmuth et al 2002)	H. sapiens	■	12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006)	H. sapiens	■	17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006)	H. sapiens	■	17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562
A complex on MINX-MS2, ATPgammaS block, glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562