Nomenclature

Gene Symbol
PPP1CA (H. sapiens)
Other Gene Symbols
MGC15877, MGC1674, PP-1A, PP1alpha, PPP1A
Full Name
protein phosphatase 1, catalytic subunit, alpha isozyme
Other Names
PPP1CA, protein phosphatase 1, catalytic subunit, alpha isoform, serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit, serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Other Resources

Entrez: Gene Info
5499
Uniprot: Protein Info
PP1A_HUMAN
Organism-Specific Database
BioGrid: Interaction Info
111493
PDB: Structures
3E7A, 3E7B, 3EGG, 3EGH, 3HVQ
SpliProt3D: Structural Model
PPP1CA

Gene Product Info

Molecular Weight (kD)
37.5
Domains
Motifs
Features
Notes

Orthologs

Name Organism
GLC7 S. cerevisiae
dis2 S. pombe
Pp1alpha-96A D. melanogaster
F56C9.1 C. elegans

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
PPP1CA CD2BP2 Y2H: Bait/Prey 0.5 22365833
PPP1CA WBP11 Y2H: Bait/Prey 0.75 22365833
PPP1CA GPKOW Y2H: Prey/Bait 1 22365833
PPP1CA PPP1CA Dervied from Literature 11588169
PPP1CA TOE1 Y2H: Prey/Bait 0.67 22365833

view interactions at SSPPIR...

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