Nomenclature

Gene Symbol
YBX1 (H. sapiens)
Other Gene Symbols
BP-8, CSDA2, CSDB, DBPB, MDR-NF1
Full Name
Y box binding protein 1
Other Names
YB-1, CBF-A, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, EFI-A, Y-box transcription factor

Other Resources

Entrez: Gene Info
4904
Uniprot: Protein Info
YBOX1_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
110959
PDB: Structures
1H95
SpliProt3D: Structural Model
YBX1

Gene Product Info

Molecular Weight (kD)
35.9
Domains
CSD
Motifs
—
Features
—
Class / Family
pre-mRNA/mRNA binding proteins
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
YBX1 LSM3 Y2H: Prey/Bait 0.75 22365833
YBX1 SMU1 Y2H: Prey/Bait 0.4 22365833
YBX1 SRSF9 Dervied from Literature — 12604611
YBX1 FUS Dervied from Literature — 12168660
YBX1 PCBP2 Dervied from Literature — 8871564
YBX1 HNRNPD Dervied from Literature — 12674497
YBX1 HNRNPK Dervied from Literature — 10809782
YBX1 RBBP6 Dervied from Literature — 18851979

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 118 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 82 27377154
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 64 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 61 21536652
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 40 27377154
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 38 20980672
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 38 21536652
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 31 27377154
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 30 18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 30 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 25 20980672
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 25 16809785
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 24 27377154
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 20 21536652
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 17 16809785
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 16 18981222
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 15 18981222
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 15 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 15 24448447
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 13 20980672
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 9 18193060
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 8 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 7 18193060
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 7 24448447
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 6 17095540
mRNP on short 5' exon, AdML, H. sapiens, (Merz et al 2007) H. sapiens 6 17095540
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 6 16809785
mRNP unspliced control, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 5 11991638
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 5 17537823
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 5 23345524
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 4 23345524
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 4 24448447
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 3 19761775
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 3 16809785
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 2 17332742
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
U11/U12 18S di-snRNP, H. sapiens, (Will et al 2004) H. sapiens ■ 15146077
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
A-like complex (A') Weri, H. sapiens, (Sharma et al 2008) H. sapiens ■ 18193060
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens ■ 12226669
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

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