Nomenclature

Gene Symbol
PPIL2 (H. sapiens)
Other Gene Symbols
CYC4, CYP60, Cyp-60, FLJ39930, MGC33174
Full Name
peptidylprolyl isomerase (cyclophilin)-like 2
Other Names
Cyclophilin60, PPIase, cyclophilin, 60kDa, cyclophilin-60, cyclophilin-like protein CyP-60, peptidyl-prolyl cis-trans isomerase-like 2

Other Resources

Entrez: Gene Info
23759
Uniprot: Protein Info
PPIL2_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
117260
PDB: Structures
1ZKC
SpliProt3D: Structural Model
PPIL2

Gene Product Info

Molecular Weight (kD)
58.8
Domains
PPIase cyclophilin-type, U-box
Motifs
—
Features
—
Complex Association
Bact complex
Class / Family
Recruited at Bact complex
Notes
—

Orthologs

Name Organism
cyp8 S. pombe
CG7747 D. melanogaster
F59E10.2 C. elegans
PPIL2 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
PPIL2 CRNKL1 Dervied from Literature — 15189447
PPIL2 ZNF830 Pull-down — 22365833
PPIL2 ZNF830 Y2H: Bidirectional 1 22365833
PPIL2 PRCC Y2H: Prey/Bait 0.5 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 124 21536652
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 62 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 59 20980672
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 29 21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 28 21536652
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 27 20980672
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 27 16809785
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 26 18322460
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 22 20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 22 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 22 24448447
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 21 18322460
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 17 24448447
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 16 24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 14 24448447
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 9 23345524
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 6 12226669
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 4 11991638
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 3 19761775
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 2 17537823
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 2 16809785
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 2 16809785
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931

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