Nomenclature

Gene Symbol
Prp31 (D. melanogaster)
Other Gene Symbols
CG6876, Dmel\CG6876, FBgn0036487, anon-EST:Liang-2.38, clone 2.38
Full Name
Prp31
Other Names
—, CG6876 gene product from transcript CG6876-RA

Other Resources

Entrez: Gene Info
39655
Uniprot: Protein Info
Q9VUM1_DROME
Organism-Specific Database
FBgn0036487
PDB: Structures
SpliProt3D: Structural Model

Gene Product Info

Molecular Weight (kD)
55.5
Domains
Motifs
Features
Complex Association
B complex, tri-snRNP, U4/U6 snRNP
Class / Family
U4/U6 snRNP
Notes

Orthologs

Name Organism
PRPF31 H. sapiens
PRP31 S. cerevisiae
prp31 S. pombe
Y110A7A.8 C. elegans

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 122 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 99 27377154
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 79 21536652
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 62 16809785
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 62 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 60 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 58 24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 53 16809785
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 44 27377154
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 42 18981222
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 39 16809785
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 39 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 33 27377154
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 31 21536652
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 27 19941820
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 27 18322460
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 27 18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 22 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 22 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 19 24448447
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 17 18981222
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 15 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 15 18981222
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 12 11804584
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 12 16809785
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 11 19941820
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 10 20980672
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 9 24448447
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 8 17537823
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 7 20980672
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 5 17537823
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 4 17095540
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 4 12226669
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 4 22110043
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 1 24448447
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae 10449419
tri-snRNP, H. sapiens, (Makarov et al 2002) H. sapiens 12411573
tri-snRNP, S. cerevisiae, (Stevens et al 1999) S. cerevisiae 11720284
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens 12176931
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens 17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens 27411562

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