Nomenclature

Gene Symbol: Prp31 (D. melanogaster)
Other Gene Symbols: CG6876, Dmel\CG6876, FBgn0036487, anon-EST:Liang-2.38, clone 2.38
Full Name: Prp31
Other Names: —, CG6876 gene product from transcript CG6876-RA

Other Resources

Entrez: Gene Info: 39655
Uniprot: Protein Info: Q9VUM1_DROME
Organism-Specific Database: FBgn0036487
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 55.5
Domains: —
Motifs: —
Features: —
Complex Association: B complex, tri-snRNP, U4/U6 snRNP
Class / Family: U4/U6 snRNP
Notes: —

Orthologs

Name	Organism
PRPF31	H. sapiens
PRP31	S. cerevisiae
prp31	S. pombe
Y110A7A.8	C. elegans

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	122	27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	99	27377154
B complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	79	21536652
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	62	16809785
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	62	27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	60	18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	58	24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	53	16809785
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	44	27377154
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	42	18981222
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	39	16809785
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	39	27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	33	27377154
tri-snRNP, H. sapiens, (Agafonov et al 2011)	H. sapiens	31	21536652
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	27	19941820
B complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	27	18322460
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	27	18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	22	18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	22	18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	19	24448447
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009)	H. sapiens	17	18981222
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009)	H. sapiens	15	18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	15	18981222
penta-snRNP, S. cerevisiae, (Stevens et al 2002)	S. cerevisiae	12	11804584
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	12	16809785
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009)	S. cerevisiae	11	19941820
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	10	18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	10	20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010)	H. sapiens	10	20980672
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	9	24448447
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	8	17537823
C complex on PM5, H. sapiens, (Bessonov et al 2010)	H. sapiens	7	20980672
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	5	17537823
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	4	18322460
mRNP on AdML, H. sapiens, (Merz et al 2007)	H. sapiens	4	17095540
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	4	12226669
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	4	22110043
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	3	12226669
Mixed complexes Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	2	18193060
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	1	24448447
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999)	S. cerevisiae	■	10449419
tri-snRNP, H. sapiens, (Makarov et al 2002)	H. sapiens	■	12411573
tri-snRNP, S. cerevisiae, (Stevens et al 1999)	S. cerevisiae	■	11720284
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005)	S. pombe	■	15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006)	H. sapiens	■	17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562