Nomenclature

Gene Symbol: pUf68 (D. melanogaster)
Other Gene Symbols: CG12085, DPUF68, Dmel\CG12085, Fir, HFP
Full Name: poly U binding factor 68kD
Other Names: —, CG12085 gene product from transcript CG12085-RA

Other Resources

Entrez: Gene Info: 38173
Uniprot: Protein Info: A4V193_DROME
Organism-Specific Database: FBgn0028577
BioGrid: Interaction Info: 63711
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 58.0
Domains: RRM, RRM 3; atypical
Motifs: —
Features: —
Complex Association: A complex
Class / Family: 17S U2 snRNP associated
Notes: —

Orthologs

Name	Organism
PUF60	H. sapiens
Y47G6A.20	C. elegans
PUF60	G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	126	21536652
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	29	18981222
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011)	H. sapiens	29	22110043
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	27	18193060
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	25	18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	20	18981222
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	19	18193060
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	17	18981222
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	16	18322460
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	16	18981222
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	15	12226669
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	13	22110043
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	12	18981222
Mixed complexes Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	11	18193060
A complex, H. sapiens, (Behzadnia et al 2007)	H. sapiens	10	17332742
EDC-E complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	10	18193060
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	9	18193060
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	9	18981222
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	8	18322460
EDC-A complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	8	18193060
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	8	18193060
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	8	27377154
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	7	18193060
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	7	27377154
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	5	12226669
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	4	27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009)	H. sapiens	3	18981222
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	3	17537823
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	3	22110043
SRM160 pulldown with BIC8 antibody, H. sapiens, (McCracken et al 2005)	H. sapiens	3	16159877
H complex, H. sapiens, (Jurica et al 2002)	H. sapiens	1	11991638
C complex, H. sapiens, (Jurica et al 2002)	H. sapiens	1	11991638
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013)	H. sapiens	1	23345524
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	1	27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	1	27377154
H complex, H. sapiens, (Sharma et al 2005)	H. sapiens	■	16109373
U2 17S, H. sapiens, (Will et al 2002)	H. sapiens	■	12234937
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
A complex on MINX-MS2, ATPgammaS block, glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562