Nomenclature
- Gene Symbol
- mle (D. melanogaster)
- Other Gene Symbols
- CG11680, Dmel\CG11680, MLE, mak, mll
- Full Name
- maleless
- Other Names
- —, CG11680 gene product from transcript CG11680-RA
Other Resources
- Entrez: Gene Info
- 35523
- Uniprot: Protein Info
- A1Z6I8_DROME
- Organism-Specific Database
- FBgn0002774
- BioGrid: Interaction Info
- 61429
- PDB: Structures
- —
- SpliProt3D: Structural Model
- —
Gene Product Info
- Molecular Weight (kD)
- 25.1
- Domains
- DRBM, Helicase ATP-binding, Helicase C-terminal
- Motifs
- DEAH box
- Features
- —
- Notes
- —
Identified in the following experiments:
| Name | Species | # Of Peptides | PubMed ID |
| Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) | H. sapiens | 150 | 27377154 |
| B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) | H. sapiens | 89 | 27377154 |
| Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) | H. sapiens | 44 | 27377154 |
| Supraspliceosome, H. sapiens, (Chen et al 2007) | H. sapiens | 43 | 17537823 |
| B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) | H. sapiens | 33 | 18981222 |
| B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) | H. sapiens | 27 | 27377154 |
| B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) | H. sapiens | 24 | 18981222 |
| Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) | H. sapiens | 16 | 27377154 |
| B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) | H. sapiens | 15 | 27377154 |
| B complex sample 2, H. sapiens, (Bessonov et al 2008) | H. sapiens | 14 | 18322460 |
| Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) | H. sapiens | 7 | 12226669 |
| mRNP on short 5' exon, AdML, H. sapiens, (Merz et al 2007) | H. sapiens | 6 | 17095540 |
| mRNP unspliced control, H. sapiens, (Merz et al 2007) | H. sapiens | 4 | 17095540 |
| E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) | H. sapiens | 4 | 22110043 |
| Supraspliceosome, G. gallus, (Chen et al 2007) | G. gallus | 3 | 17537823 |
| mRNP on AdML, H. sapiens, (Merz et al 2007) | H. sapiens | 2 | 17095540 |
| C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) | H. sapiens | 1 | 18322460 |
| Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) | H. sapiens | 1 | 12226669 |
| P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) | H. sapiens | 1 | 23345524 |
| Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) | H. sapiens | ■ | 12176931 |
| A complex, H. sapiens, (Hartmuth et al 2002) | H. sapiens | ■ | 12477934 |
| PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) | H. sapiens | ■ | 17114945 |
| PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) | H. sapiens | ■ | 17114945 |
