Nomenclature

Gene Symbol
HNRNPU (H. sapiens)
Other Gene Symbols
HNRPU, SAF-A, U21.1, hnRNP U
Full Name
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Other Names
hnRNP U, heterogeneous nuclear ribonucleoprotein U, p120 nuclear protein, pp120, scaffold attachment factor A

Other Resources

Entrez: Gene Info
3192
Uniprot: Protein Info
HNRPU_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
109433
PDB: Structures
1ZRJ
SpliProt3D: Structural Model
HNRNPU

Gene Product Info

Molecular Weight (kD)
90.6
Domains
B30.2/SPRY, SAP
Motifs
—
Features
—
Class / Family
hnRNP
Notes
—

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
HNRNPU HNRNPD Y2H: Bait/Prey 0.75 22365833
HNRNPU HNRNPH3 Y2H: Prey/Bait 0.5 22365833
HNRNPU SYNCRIP Y2H: Bait/Prey 0.75 22365833
HNRNPU SMN1 Dervied from Literature — 8670859

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 60 18193060
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 51 21536652
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 40 18193060
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 35 18193060
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 29 17537823
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 25 27377154
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 20 18193060
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 14 18322460
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 13 18193060
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 13 11991638
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 13 18193060
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 11 27377154
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 10 17537823
SKIP GST-tag pulldown, H. sapiens, (Zhang et al 2003) H. sapiens 8 12840015
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 7 17332742
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 7 22110043
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 6 18981222
mRNP unspliced control, H. sapiens, (Merz et al 2007) H. sapiens 5 17095540
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 4 18981222
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 4 22110043
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007) H. sapiens 3 17095540
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 3 22110043
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 3 24448447
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 3 27377154
H complex, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 2 24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 2 27377154
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 1 17095540
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 1 19761775
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934

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