Nomenclature

Gene Symbol: GCFC1 (H. sapiens)
Other Gene Symbols: BM020, C21orf66, FLJ90561, FSAP105, GCFC
Full Name: GC-rich sequence DNA-binding factor 1
Other Names: C21orf66, GC-rich sequence DNA-binding factor 1, GC-rich sequence DNA-binding factor candidate, functional spliceosome-associated protein 105

Other Resources

Entrez: Gene Info: 94104
Uniprot: Protein Info: GCFC1_HUMAN
Organism-Specific Database: —
BioGrid: Interaction Info: 125115
PDB: Structures: —
SpliProt3D: Structural Model: GCFC

Gene Product Info

Molecular Weight (kD): 104.8
Domains: —
Motifs: —
Features: —
Class / Family: pre-mRNA/mRNA binding proteins
Notes: —

Orthologs

Name	Organism
CG1965	D. melanogaster
F43G9.12	C. elegans
GCFC1	G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	71	27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	39	27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010)	H. sapiens	38	20980672
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	37	27377154
C complex on PM5, H. sapiens, (Bessonov et al 2010)	H. sapiens	36	20980672
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	19	18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	19	24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	15	18322460
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	15	27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	15	27377154
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	14	18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	13	20980672
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	13	24448447
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	11	27377154
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	8	18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	8	24448447
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010)	H. sapiens	7	20980672
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	7	18981222
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	6	12226669
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	6	18981222
C complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	4	18322460
C complex on PM5, H. sapiens, (Agafonov et al 2011)	H. sapiens	4	21536652
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	3	17537823
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	3	12226669
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	3	18981222
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	3	18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	3	18981222
C complex, H. sapiens, (Jurica et al 2002)	H. sapiens	2	11991638
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009)	H. sapiens	2	18981222
C complex exons trimmed, H. sapiens, (Ilagan et al 2009)	H. sapiens	1	19761775
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	1	18981222
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	■	24448447