Nomenclature

Gene Symbol: THOC2 (H. sapiens)
Other Gene Symbols: CXorf3, THO2, dJ506G2.1, hTREX120
Full Name: THO complex 2
Other Names: hTHO2, THO complex subunit 2

Other Resources

Entrez: Gene Info: 57187
Uniprot: Protein Info: THOC2_HUMAN
Organism-Specific Database: —
BioGrid: Interaction Info: 121436
PDB: Structures: —
SpliProt3D: Structural Model: THOC2

Gene Product Info

Molecular Weight (kD): 182.8
Domains: —
Motifs: Nuclear localization signal
Features: —
Class / Family: TREX
Notes: —

Orthologs

Name	Organism
THO2	S. cerevisiae
tho2	D. melanogaster
C16A3.8	C. elegans
THOC2	G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	22	18322460
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	20	27377154
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	14	17537823
C complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	14	18322460
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010)	H. sapiens	12	20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010)	H. sapiens	12	20980672
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	12	12226669
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	11	27377154
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	10	24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	9	27377154
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	9	27377154
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	7	12226669
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	7	27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	6	27377154
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	5	17537823
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010)	H. sapiens	4	20980672
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	4	24448447
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	3	18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	3	20980672
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	3	24448447
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	2	18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	2	24448447
mRNP on BetaGlobin, H. sapiens, (Merz et al 2007)	H. sapiens	1	17095540
mRNP on AdML, H. sapiens, (Merz et al 2007)	H. sapiens	1	17095540
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931