Nomenclature

Gene Symbol
UPF1 (H. sapiens)
Other Gene Symbols
FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1
Full Name
UPF1 regulator of nonsense transcripts homolog (yeast)
Other Names
Upf1, ATP-dependent helicase RENT1, UP Frameshift 1, delta helicase, nonsense mRNA reducing factor 1, regulator of nonsense transcripts 1

Other Resources

Entrez: Gene Info
5976
Uniprot: Protein Info
RENT1_HUMAN
Organism-Specific Database
BioGrid: Interaction Info
111908
PDB: Structures
2GJK, 2GK6, 2GK7, 2IYK, 2WJV
SpliProt3D: Structural Model

Gene Product Info

Molecular Weight (kD)
124.3
Domains
Motifs
[ST]-Q motif 1, [ST]-Q motif 2
Features
Class / Family
EJC/mRNP
Notes

Orthologs

Name Organism
NAM7 S. cerevisiae
upf1 S. pombe
Upf1 D. melanogaster
Y48G8AL.6 C. elegans
UPF1 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 3 17537823

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