Nomenclature

Gene Symbol: Hsc70-1 (D. melanogaster)
Other Gene Symbols: 143191_at, BcDNA:RH49358, CG8937, Dmel\CG8937, HSC-70
Full Name: Heat shock protein cognate 1
Other Names: —, CG8937 gene product from transcript CG8937-RC

Other Resources

Entrez: Gene Info: 39542
Uniprot: Protein Info: HSP7A_DROME
Organism-Specific Database: FBgn0001216
BioGrid: Interaction Info: 64882
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 70.7
Domains: —
Motifs: —
Features: —
Complex Association: C complex, P complex
Class / Family: PRP19 complex
Notes: —

Orthologs

Name	Organism
HSPA8	H. sapiens
SSA4	S. cerevisiae
F26D10.3	C. elegans
HSPA8	G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	32	16809785
C complex on PM5, H. sapiens, (Agafonov et al 2011)	H. sapiens	27	21536652
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	27	27377154
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010)	H. sapiens	24	20980672
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010)	H. sapiens	23	20980672
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	22	17537823
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	22	18193060
C complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	20	18322460
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	20	16809785
C complex, H. sapiens, (Ilagan et al 2009)	H. sapiens	19	19761775
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013)	H. sapiens	19	23345524
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	19	24448447
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013)	H. sapiens	18	23345524
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	17	24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	17	27377154
EDC-A complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	13	18193060
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	13	27377154
C complex exons trimmed, H. sapiens, (Ilagan et al 2009)	H. sapiens	10	19761775
C complex, H. sapiens, (Jurica et al 2002)	H. sapiens	10	11991638
Mixed complexes Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	9	18193060
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008)	H. sapiens	9	18322460
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	9	27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	8	18322460
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011)	H. sapiens	8	21536652
C complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	7	18322460
H complex, H. sapiens, (Jurica et al 2002)	H. sapiens	7	11991638
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	7	18193060
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	7	24448447
A complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	6	21536652
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009)	H. sapiens	5	18981222
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	5	18193060
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	5	16809785
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	4	17537823
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009)	H. sapiens	4	18981222
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	3	18193060
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	3	18193060
EDC-E complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	3	18193060
B complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	3	21536652
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	3	24448447
A complex, H. sapiens, (Behzadnia et al 2007)	H. sapiens	2	17332742
E complex Weri, H. sapiens, (Sharma et al 2005)	H. sapiens	■	16109373
penta-snRNP, S. cerevisiae, (Stevens et al 2002)	S. cerevisiae	■	11804584
H complex Weri, H. sapiens, (Sharma et al 2005)	H. sapiens	■	16109373
B* complex, H. sapiens, (Makarov et al 2002)	H. sapiens	■	12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	■	12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	■	12226669
CDC5L pulldown, H. sapiens, (Ajuh et al 1999)	H. sapiens	■	11101529
Clf1p-pulldown, S. cerevisiae, (Wang et al 2003)	S. cerevisiae	■	12509417