Nomenclature

Gene Symbol
RBM17 (H. sapiens)
Other Gene Symbols
DKFZp686F13131, MGC14439, SPF45
Full Name
RNA binding motif protein 17
Other Names
SPF45, 45 kDa-splicing factor, RNA-binding motif protein 17, splicing factor 45, splicing factor 45kDa

Other Resources

Entrez: Gene Info
84991
Uniprot: Protein Info
SPF45_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
124416
PDB: Structures
2PE8, 2PEH
SpliProt3D: Structural Model
RBM17

Gene Product Info

Molecular Weight (kD)
45.0
Domains
G-patch, RRM
Motifs
—
Features
—
Complex Association
A complex
Class / Family
17S U2 snRNP associated
Notes
—

Orthologs

Name Organism
Spf45 D. melanogaster
F58B3.7 C. elegans
RBM17 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
RBM17 SF3B1 Y2H: Bait/Prey 0.5 22365833
RBM17 SF3B1 Pull-down — 22365833
RBM17 SF3B1 Dervied from Literature — 17589525
RBM17 DHX15 Pull-down — 22365833
RBM17 DHX15 Y2H: Prey/Bait 1 22365833
RBM17 U2AF2 Dervied from Literature — 17589525
RBM17 U2SURP Y2H: Prey/Bait 0.67 22365833
RBM17 SF1 Dervied from Literature — 17589525
RBM17 SF1 Y2H: Bidirectional 0.94 22365833
RBM17 CWC15 Y2H: Prey/Bait 0.5 22365833
RBM17 SUGP1 Y2H: Bait/Prey 0.62 22365833
RBM17 SUGP1 Pull-down — 22365833
RBM17 SAP30BP Y2H: Bidirectional 1 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 102 21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 42 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 20 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 19 18322460
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 18 27377154
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 15 27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 14 27377154
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 12 21536652
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 11 27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 10 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 9 18322460
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 8 17537823
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 8 22110043
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 8 24448447
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 7 18193060
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 5 16809785
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 4 17332742
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 4 20980672
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 4 24448447
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 2 20980672
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 2 16809785
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 1 20980672
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 1 23345524
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens ■ 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens ■ 24448447

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