Nomenclature

Gene Symbol
Y49E10.15 (C. elegans)
Other Gene Symbols
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Full Name
Small Nuclear Ribonucleoprotein family member (snr-6)
Other Names
—, Y49E10.15

Other Resources

Entrez: Gene Info
176668
Uniprot: Protein Info
RUXE_CAEEL
Organism-Specific Database
WBGene00004919
PDB: Structures
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SpliProt3D: Structural Model
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Gene Product Info

Molecular Weight (kD)
10.6
Domains
—
Motifs
—
Features
—
Complex Association
17S U2 snRNP, A complex, B complex, Bact complex, C complex, P complex, tri-snRNP, U1 snRNP, U4/U6 snRNP, U5 snRNP
Class / Family
Sm
Notes
—

Orthologs

Name Organism
SNRPE H. sapiens
SME1 S. cerevisiae
sme1 S. pombe
SmE D. melanogaster
MAL13P1.253 P. falciparum
SNRPE G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 434 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 336 21536652
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 295 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 257 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 213 21536652
U1 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 201 21536652
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 162 21386897
17S U2 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 147 21536652
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 101 21386897
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 70 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 65 27377154
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 45 16809785
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 39 21386897
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 31 27377154
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 28 16809785
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 25 18322460
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 25 27377154
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 24 18322460
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 23 18322460
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 22 16809785
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 22 24448447
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 21 24448447
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 18 20980672
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 18 24448447
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 18 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 17 27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 14 20980672
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 14 19935684
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 12 20980672
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 11 18981222
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 10 24448447
A complex, H. sapiens, (Behzadnia et al 2007) H. sapiens 9 17332742
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 9 18981222
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 9 18981222
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 8 19761775
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 8 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 8 18981222
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 7 19941820
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 7 23431055
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 6 19941820
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 6 20980672
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 5 19941820
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 5 17537823
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 5 18981222
EDC-E complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 5 19935684
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 4 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 4 19935684
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 4 23431055
CACN-1 pulldown with FLAG-HA tandem affinity from C. elegans, C. elegans, (Doherty et al 2014) C. elegans 4 24948787
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 3 19761775
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 3 23345524
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 2 19941820
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 2 17537823
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 2 23345524
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011) H. sapiens 2 22110043
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 1 11804584
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 1 16809785
Clf1p-pulldown, S. cerevisiae, (Wang et al 2003) S. cerevisiae 1 12509417
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 1 21526149
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
U11/U12 18S di-snRNP, H. sapiens, (Will et al 2004) H. sapiens ■ 15146077
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae ■ 10449419
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
A-like complex (A') Weri, H. sapiens, (Sharma et al 2008) H. sapiens ■ 18193060
tri-snRNP, S. cerevisiae, (Stevens et al 1999) S. cerevisiae ■ 11720284
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
U1 snRNP, S. pombe, (Newo et al 2007) S. pombe ■ 17264129
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe ■ 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
PSF-pulldown, with AdMl splicing subtrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

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