Nomenclature

Gene Symbol: U2af50 (D. melanogaster)
Other Gene Symbols: 9-21, CG9998, DU2AF50, DmU2AF[50], Dmel\CG9998
Full Name: U2 small nuclear riboprotein auxiliary factor 50
Other Names: —, CG9998 gene product from transcript CG9998-RA

Other Resources

Entrez: Gene Info: 32602
Uniprot: Protein Info: U2AF2_DROME
Organism-Specific Database: FBgn0005411
BioGrid: Interaction Info: 58942
PDB: Structures: —
SpliProt3D: Structural Model: —

Gene Product Info

Molecular Weight (kD): 46.7
Domains: RRM
Motifs: —
Features: —
Complex Association: A complex
Class / Family: 17S U2 snRNP associated
Notes: —

Orthologs

Name	Organism
U2AF2	H. sapiens
MUD2	S. cerevisiae
prp2	S. pombe
Y92C3B.2	C. elegans
PF14_0656	P. falciparum

View orthologs at Homologene

Identified in the following experiments:

Name	Species	# Of Peptides	PubMed ID
A complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	69	21536652
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	45	27377154
B complex on MINX, H. sapiens, (Agafonov et al 2011)	H. sapiens	43	21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	36	27377154
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	32	24448447
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	20	27377154
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	19	27377154
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	18	16809785
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011)	H. sapiens	14	22110043
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015)	H. sapiens	14	27377154
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	11	18981222
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	11	16809785
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	9	18981222
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	8	18193060
B complex sample 1, H. sapiens, (Bessonov et al 2008)	H. sapiens	8	18322460
EDC-E complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	8	18193060
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009)	D. melanogaster	8	18981222
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009)	D. melanogaster	8	18981222
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015)	H. sapiens	8	27377154
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	7	18193060
Supraspliceosome, H. sapiens, (Chen et al 2007)	H. sapiens	7	17537823
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	7	18193060
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009)	D. melanogaster	7	18981222
E complex IP'd by antibody to U1A, H. sapiens, (Marakov et al 2011)	H. sapiens	7	22110043
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002)	H. sapiens	6	12226669
A complex, H. sapiens, (Behzadnia et al 2007)	H. sapiens	5	17332742
H complex, H. sapiens, (Jurica et al 2002)	H. sapiens	5	11991638
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006)	H. sapiens	5	16809785
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	5	19935684
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	5	24448447
B complex sample 2, H. sapiens, (Bessonov et al 2008)	H. sapiens	4	18322460
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	3	18193060
EDC-A complex Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	3	18193060
A-like complex (A') HeLa, H. sapiens, (Sharma et al 2008)	H. sapiens	2	18193060
Mixed complexes Weri, H. sapiens, (Sharma et al 2008)	H. sapiens	2	18193060
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002)	H. sapiens	2	12226669
Supraspliceosome, G. gallus, (Chen et al 2007)	G. gallus	2	17537823
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006)	H. sapiens	2	16809785
Bact complex, deltaPrp2 on M3Actin, Q-Tof, 1 pmol, S. cerevisiae, (Warkocki et al 2009)	S. cerevisiae	2	19935684
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014)	H. sapiens	2	24448447
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014)	H. sapiens	1	24448447
U2 17S, H. sapiens, (Will et al 2002)	H. sapiens	■	12234937
E complex Weri, H. sapiens, (Sharma et al 2005)	H. sapiens	■	16109373
H complex Weri, H. sapiens, (Sharma et al 2005)	H. sapiens	■	16109373
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999)	H. sapiens	■	9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002)	H. sapiens	■	12176931
A complex, H. sapiens, (Hartmuth et al 2002)	H. sapiens	■	12477934
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006)	H. sapiens	■	17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562
A complex on MINX-MS2, ATPgammaS block, glycerol gradient peak, H. sapiens, (Agafonov et al 2016)	H. sapiens	■	27411562